Evidence map›Paper›PMID 39881394›Full record

ArticleMicrobial cell factories2025

Turning residues into valuable compounds: organic waste conversion into odd-chain fatty acids via the carboxylate platform by recombinant oleaginous yeast.

Marta de Vicente, Cristina Gonzalez-Fernández, Jean Marc Nicaud, Elia Tomás-Pejó

Abstract read
In one paragraph

Article in Microbial cell factories, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. A circulating odd-chain fatty acid biomarker signature discriminates pediatric allergic rhinitis with asthma from related allergic airway phenotypes.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Article
  2. Recent advances in microbial production of odd-chain fatty acids.World journal of microbiology & biotechnology · 2026
    Review
  3. Sustainable Lipid Production withMicroorganisms · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marta de VicenteBiotechnological Processes Unit, IMDEA Energy, 28935, Móstoles (Madrid), Spain.ORCID http://orcid.org/0000-0001-8182-8608
Cristina Gonzalez-FernándezBiotechnological Processes Unit, IMDEA Energy, 28935, Móstoles (Madrid), Spain. Cristina.gonzalez@imdea.org.ORCID http://orcid.org/0000-0002-0824-9252
Jean Marc NicaudUniversité Paris Saclay, INRAE, AgroParis Tech, Micalis Institute, 78350, Jouy-en-Josas, France.ORCID http://orcid.org/0000-0002-6679-972X
Elia Tomás-PejóBiotechnological Processes Unit, IMDEA Energy, 28935, Móstoles (Madrid), Spain.ORCID http://orcid.org/0000-0003-3554-4510

Funding

Ministerio de Ciencia e Innovación PRE2021-100022Ministerio de Economía y Competitividad PID2020-119403RB-C21
6 · The paper itself

Abstract

Environmental concerns are rising the need to find cost-effective alternatives to fossil oils. In this sense, short-chain fatty acids (SCFAs) are proposed as carbon source for microbial oils production that can be converted into oleochemicals. This investigation took advantage of the outstanding traits of recombinant Yarrowia lipolytica strains to assess the conversion of SCFAs derived from real digestates into odd-chain fatty acids (OCFA). High yeast OCFAs content was aimed by using two engineered strains (Y. lipolytica JMY7780 and JMY7782). Batch and two-step batch fermentations were performed, reaching high lipid content (40.8% w/w) and lipid yield (0.07 g/g) with JMY7782, which overexpresses propionyl-CoA synthase. Fed-batch fermentation with an acetic acid pulse after 24 h was also carried out to promote SCFAs consumption and OCFAs production. In this case, SCFAs consumption rate increased and JMY7782 was able to accumulate up to 60.4% OCFAs of the total lipids produced from food waste-derived carbon sources.

Indexed as

Fatty AcidsFatty Acids, VolatileYarrowiaFermentationMetabolic EngineeringFatty AcidsFatty Acids, VolatileLipidsOdd-chain fatty acidsOleaginous yeastsShort-chain fatty acidsYarrowia lipolytica

Identifiers

PMID39881394
PMCPMC11776196

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.