Evidence map›Paper›PMID 39881311›Full record

ArticleNutrition journal2025

Association between early dietary patterns and cardiometabolic health at age 8: a confirmatory analysis of the European Childhood Obesity Project.

Mariona Gispert-Llauradó, Joaquin Escribano, Natalia Ferré, Veit Grote, Berthold Koletzko, Gina Ambrosini, Elvira Verduci, Dariusz Gruszfeld, Annick Xhonneux, Veronica Luque

Abstract read
In one paragraph

Article in Nutrition journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Nutritional Status and Nutrient Intake of Children With Feeding Disorders in Early Childhood.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Article
  7. Observational
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mariona Gispert-LlauradóPaediatrics, Nutrition and Development Research Unit, Universitat Rovira i Virgili. Reus, Tarragona, Spain.
Joaquin EscribanoPaediatrics, Nutrition and Development Research Unit, Universitat Rovira i Virgili. Reus, Tarragona, Spain. joaquin.escribano@urv.cat.
Natalia FerréPaediatrics, Nutrition and Development Research Unit, Universitat Rovira i Virgili. Reus, Tarragona, Spain.
Veit GroteDepartment of Paediatrics, Dr. von Hauner Children's Hospital, LMU - Ludwig Maximilians Universität Munich, LMU University Hospitals, München, Germany.
Berthold KoletzkoDepartment of Paediatrics, Dr. von Hauner Children's Hospital, LMU - Ludwig Maximilians Universität Munich, LMU University Hospitals, München, Germany.
Gina AmbrosiniSchool of Population and Global Health, University of Western Australia, Clifton Street Building, Clifton St, 6009, Nedlands, Perth, WA, Australia.
Elvira VerduciMetabolic Diseases Unit, Department of Paediatrics, Vittore Buzzi Children's Hospital, University of Milan, Via Lodovico Castelvetro, 32, 20154, Milano, MI, Italy.
Dariusz GruszfeldNeonatal Department, Children's Memorial Health Institute, Al. Dzieci Polskich 20, 04-730, Warsaw, Poland.
Annick XhonneuxGroupe Santé CHC, bd Patience et Beaujonc 2 ‑ (B), 4000, Liège, Belgium.
Veronica LuquePaediatrics, Nutrition and Development Research Unit, Universitat Rovira i Virgili. Reus, Tarragona, Spain. veronica.luque@urv.cat.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND &

aimMetabolic and cardiovascular health outcomes are strongly influenced by diet. Dietary habits established in early childhood may persist into adulthood. This study aimed to examine the association between dietary patterns at both 2 and 8 years of age, explaining the maximum variability of high- and low-quality fats, sugars, and fibre, and cardiometabolic markers at age 8 years.

methodsThis was a secondary analysis of the European Childhood Obesity Project, formerly a randomized clinical trial across five European countries performed in healthy term newborns. Children in the study were categorized at ages 2 and 8 years into two groups based on cluster analysis of dietary patterns (DP) derived from Reduction Rank Regression (RRR). A cross-sectional and prospective analysis was conducted to evaluate the associations between these DPs and cardiometabolic outcomes, including body mass index (BMI), blood pressure (BP), and biochemical markers. Triglycerides, HDL cholesterol and insulin resistance index (HOMA-IR) were also categorized as altered versus normal values. Asociations between dietary patterns and health outcomes were assessed using linear and logistic regression models, adjusting for covariates based on a step-wise approach.

resultsA total of 336 children were classified based on quality of nutrient intakes into either a "Poor-Quality dietary pattern" (PQ-DP) (48% and 66% of infants at 2 and 8 years, respectively) or the "Health-Conscious dietary pattern" (HC-DP) (52% and 34% of infants at 2 and 8 years, respectively). Following a PQ-DP at both ages 2 and 8 was associated with higher triglycerides (β = 0.061, p = 0.049), systolic and diastolic BP (β = 13.019, p < 0.001 & β = 7.612, p = 0.014, respectively) and altered levels of HOMA-IR (OR = 3.1, p = 0.037, 95% CI = 1.1-9.1) at 8 years, compared to children with an HC-DP at both ages, after adjusting for confounders.

conclusionAdherence to a dietary pattern with a poorer nutritional profile in early childhood and school age is associated with worse cardiometabolic risk markers at 8 years old.

Indexed as

DietFeeding BehaviorPediatric ObesityBiomarkersBlood PressureBody Mass IndexCardiometabolic Risk FactorsChildChild, PreschoolCross-Sectional StudiesEuropeFemaleHumansInsulin ResistanceMaleProspective StudiesBiomarkersTriglyceridesCardiometabolic healthClusterEarly childhood nutritionPoor quality dietary patternProspective analysesReduction rank regression

Identifiers

PMID39881311
PMCPMC11776328

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.