Evidence map›Paper›PMID 39881284›Full record

ArticleBMC public health2025

Ambient air pollution and Alzheimer's disease and other dementias: a global study between 1990 and 2019.

Cui Guo, Dongze Wu, Jun Yang, Xingcheng Lu, Xiang Yan Chen, Jun Ma, Changqing Lin, Alexis K H Lau, Yingzhao Jin, Ruiyun Li and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Cui GuoDepartment of Urban Planning and Design, the University of Hong Kong, 8/F, Knowles Building, Pokfulam Road, Hong Kong SAR, China. cuiguo@hku.hk.ORCID 0000-0003-0816-6534
Dongze WuDepartment of Rheumatology and Immunology, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China. dongze_wu@163.com.
Jun YangSchool of Public Health, Guangzhou Medical University, Guangzhou, China.
Xingcheng LuDepartment of Geography and Resource Management, the Chinese University of Hong Kong, Hong Kong SAR, China.
Xiang Yan ChenDivision of Science, Engineering, and Health Studies, College of Professional and Continuing Education, Hong Kong Polytechnic University, Hong Kong SAR, China.
Jun MaDepartment of Urban Planning and Design, the University of Hong Kong, 8/F, Knowles Building, Pokfulam Road, Hong Kong SAR, China.
Changqing LinAnhui Institute of Optics and Fine Mechanics, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei , China.
Alexis K H LauDepartment of Civil and Environmental Engineering, the Hong Kong University of Science and Technology, Hong Kong SAR, China.
Yingzhao JinDepartment of Medicine and Therapeutics, The Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, China.
Ruiyun LiKey Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, 211166, Nanjing, China. ruiyun.li@njmu.edu.cn.
Shenjing HeDepartment of Urban Planning and Design, the University of Hong Kong, 8/F, Knowles Building, Pokfulam Road, Hong Kong SAR, China.

Funding

Natural Science Foundation for Young Scientists of Shanxi Province 42407563Seed Fund for Basic Research for New Staff 2022/23 2201100253Seed Fund for Collaborative Research 2207101523
6 · The paper itself

Abstract

backgroundEmerging research found air pollution may be associated with incident Alzheimer's disease (AD) and other dementias. However, few studies have examined these associations at the global scale. This study aimed to assess the dynamic associations between ambient air pollution and the burden of AD and other dementias worldwide.

methodsThis study synthesised 149 countries/territories between 1990 and 2019. These data include age-standardised mortality rate (ASMR) and disability-adjusted life-years (DALYs) of AD and other dementias, ambient air pollution (fine particulate matter [PM

resultsDuring 1990-2019, the global ASMR, DALYs and O

conclusionsThe burden of dementia is expected to increase globally, given the continuously expansion of the ageing population. Air pollution was found to be significantly associated with a higher burden of AD and dementia. As a persistent challenge in urban cities, air pollution demands strict regulatory control.

Indexed as

Air PollutionAlzheimer DiseaseDementiaEnvironmental ExposureGlobal HealthAir PollutantsDisability-Adjusted Life YearsHumansParticulate MatterAir PollutantsParticulate MatterAir pollutionAlzheimer’s disease and other dementiasGlobal burden of Disease studyHealthy ageing citiesInequity

Identifiers

PMID39881284
PMCPMC11781054

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.