Evidence map›Paper›PMID 39881272›Full record

SynthesisBMC pulmonary medicine2025

Cannabis consumption and risk of asthma: a systematic review and meta-analysis.

Ajay Malvi, Mahalaqua Nazli Khatib, Ashok Kumar Balaraman, R Roopashree, Mandeep Kaur, Manish Srivastava, Amit Barwal, G V Siva Prasad, Pranchal Rajput, Rukshar Syed and 12 more

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC pulmonary medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Is There a Place for Cannabinoids in Asthma Treatment?International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Ajay Malvi *Department of Pharmacy Practice, National Institute of Pharmaceutical Education and Research, Guwahati, 781101, India.
Mahalaqua Nazli Khatib *Division of Evidence Synthesis, Global Consortium of Public Health and Research, Datta Meghe Istitute of Higher Education, Wardha, India.
Ashok Kumar BalaramanResearch and Enterprise, University of Cyberjaya, Persiaran Bestari, Cyber 11, Cyberjaya, Selangor, 63000, Malaysia.
R RoopashreeDepartment of Chemistry and Biochemistry, School of Sciences, JAIN (Deemed to be University), Bangalore, Karnataka, India.
Mandeep KaurDepartment of Allied Healthcare and Sciences, Vivekananda Global University, Jaipur, Rajasthan, 303012, India.
Manish SrivastavaDepartment of Endocrinology, NIMS University, Jaipur, India.
Amit BarwalChandigarh Pharmacy College, Chandigarh Group of College, Jhanjeri, Mohali, Punjab, 140307, India.
G V Siva PrasadDepartment of Chemistry, Raghu Engineering College, Visakhapatnam, Andhra Pradesh, 531162, India.
Pranchal RajputSchool of Applied and Life Sciences, Division of Research and Innovation, Uttaranchal University, Dehradun, India.
Rukshar SyedIES Institute of Pharmacy, IES University, Bhopal, Madhya Pradesh, 462044, India.
Gajendra SharmaNew Delhi Institute of Management, Delhi, India.
Sunil KumarDepartment of Microbiology, Graphic Era (Deemed to be University), Clement Town Dehradun, 248002, India.
Mahendra Pratap SinghCenter for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
Ganesh BushiSchool of Pharmaceutical Sciences, Lovely Professional University, Phagwara, India.
Nagavalli ChilakamNoida Institute of Engineering and Technology (Pharmacy Institute), Greater Noida, India.
Sakshi PandeyCentre of Research Impact and Outcome, Chitkara University, Rajpura, Punjab, 140417, India.
Manvinder BrarChitkara Centre for Research and Development, Chitkara University, Himachal Pradesh, 174103, India.
Rachana MehtaClinical Microbiology, RDC, Manav Rachna International Institute of Research and Studies, Faridabad, Haryana, 121004, India.
Sanjit SahDepartment of Paediatrics, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra, 411018, India.
Abhay M GaidhaneJawaharlal Nehru Medical College, and Global Health Academy, School of Epidemiology and Public Health, Datta Meghe Institute of Higher Education, Wardha, India.
Muhammed ShabilUniversity Center for Research and Development, Chandigarh University, Mohali, Punjab, India.
Afukonyo Shidoiku DanielGlobal Health and Infectious Diseases Control Institute, Nasarawa State University, Keffi, Nigeria. afukonyoshidoiku@tsuniversity.edu.ng.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCannabis is the third most widely used psychoactive substance globally, and its consumption has been increasing, particularly with the growing trend of legalization for medicinal and recreational use. Recent studies have raised concerns about the potential impact of cannabis on respiratory health, specifically the risk of asthma, a significant public health concern. This systematic review aimed to consolidate research on the association between cannabis use and the risk of asthma.

methodsA comprehensive search was conducted across PubMed, Embase, and Web of Science, covering studies published up to September 30, 2024. We included peer-reviewed observational studies evaluating the link between cannabis consumption and the risk of asthma diagnosis. Data synthesis employed a random-effects meta-analysis to account for heterogeneity. R statistical software (version 4.4) was used for statistical analyses.

resultsThe search yielded 8 relevant studies after screening 1,887 records. The pooled odds ratio (OR) for the association between cannabis consumption and the risk of asthma diagnosis was 1.31, 95% confidence interval (CI): 1.19-1.44, indicating greater odds of having asthma compared to non-users. Moderate heterogeneity was observed (I² = 46%), and sensitivity analysis confirmed the robustness of the findings.

conclusionThis systematic review and meta-analysis identifies a significant association between cannabis use and greater odds of having asthma. These findings emphasize the importance of raising awareness about the potential respiratory risks associated with cannabis use. Future research should prioritize identifying moderating factors, such as the frequency and mode of cannabis consumption, to enhance understanding of this association and provide a stronger evidence base for potential public health interventions. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

AsthmaCannabisMarijuana SmokingHumansRisk FactorsAsthmaCannabisMeta-analysisRespiratory healthSystematic review

Identifiers

PMID39881272
PMCPMC11780798

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.