ArticleBMC women's health2025
How does BMI correlate with menarche onset? Evidence from the Italian HBSC cross-sectional study.
Article in BMC women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Hypothalamic neuroimmune remodeling as an immunometabolic bridge between childhood obesity and earlier pubertal onset.Frontiers in immunology · 2026Review
- Age at menarche and chronological age as explanatory factors of BMI: a cross-sectional study among Peruvian adolescents.BMC women's health · 2025Article
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Authors and funding
8 authors.
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Abstract
backgroundMenarche is an important period in a female's life; its time of onset may depend on various factors and could correlate with the development of diseases in adulthood. Our study aims to investigate the relationship between body mass index and age at onset of menarche;
methodsWe used a unique standardized national dataset on adolescent girls participating in the Italian Health Behaviour in School-aged Children Study. Two independent nationally representative survey datasets: one on 15-year-olds (n = 6505, year 2017/2018) and one on 11-year-olds (n = 6548, year 2013/2014) were analysed. The survey instrument was the self-report questionnaire. Median age at menarche and 95% confidence intervals were estimated through Kaplan-Meier analysis. Hierarchical models assessed the relationship between BMI and age at menarche;
resultsRegion-level median age at menarche ranged between 12 years/5 months and 13 years/4 months. Region-level prevalence of overweight among 15-year-old girls ranged between 6% and 24%. Age at menarche was inversely associated with individual BMI (unstandardized regression coefficient beta=-0.81; 95% CI, -0.92 to -0.70). Individual-level and class-level measures of BMI accounted for 215.2% of the region-level variance in age at menarche;
conclusionsThe results show that girls who were overweight during childhood went through early puberty. Further investigation needs to assess a possible cause-effect relationship.
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