ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2025
Understanding the unique patient-causal singularism and patient reported outcomes.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Patient reported outcome measures (PROMs) now play a significant role in randomized control trials (RCTs) providing the basis for efficacy or safety endpoints. Most PROM data is quantitative and is summarized at the group level. Whilst PROM data is informative in providing the aggregated patient perspective on disease and interventions, it provides little information about the patients' individual experiences. For this, qualitative 'case study' research is needed. However, qualitative case-study research has traditionally not been considered as robust for establishing causal inference due to its singular nature and lack of quantifiable findings. The focus of this paper was to advance a proposal as to how to produce a single mixed-methods case analysis of an individual's experiences with treatment from PROM and narrative data that can be used in causal inference research; so-called "Causal singularism".
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