Evidence map›Paper›PMID 39881008›Full record

ArticleEuropean radiology experimental2025

Photon-counting detector CTA to assess intracranial stents and flow diverters: an in vivo study with ultrahigh-resolution spectral reconstructions.

Frederic De Beukelaer, Sophie De Beukelaer, Laura L Wuyts, Omid Nikoubashman, Mohammed El Halal, Iliana Kantzeli, Martin Wiesmann, Hani Ridwan, Charlotte S Weyland

Abstract read
In one paragraph

Article in European radiology experimental, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Photon-Counting CT for Evaluation of Coiled Intracranial Aneurysms.AJNR. American journal of neuroradiology · 2026
    Article
  6. Article
  7. Review
  8. Photon-counting detector CT angiography to evaluate carotid and subclavian artery stents and compared to ultrasound and angiography - an in-vivo study with spectral reconstructions.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Frederic De BeukelaerDepartment of Neuroradiology, University hospital RWTH Aachen, Aachen, Germany.
Sophie De BeukelaerDepartment of Neurology, Inselspital, University hospital Bern, Bern, Switzerland.
Laura L WuytsDepartment of Radiology, AZ Sint-Lucas, Ghent, Belgium.
Omid NikoubashmanDepartment of Neuroradiology, University hospital RWTH Aachen, Aachen, Germany.
Mohammed El HalalDepartment of Neuroradiology, University hospital RWTH Aachen, Aachen, Germany.
Iliana KantzeliDepartment of Neuroradiology, University hospital RWTH Aachen, Aachen, Germany.
Martin WiesmannDepartment of Neuroradiology, University hospital RWTH Aachen, Aachen, Germany.
Hani RidwanDepartment of Neuroradiology, University hospital RWTH Aachen, Aachen, Germany.
Charlotte S WeylandDepartment of Neuroradiology, University hospital RWTH Aachen, Aachen, Germany. cweyland@ukaachen.de.ORCID http://orcid.org/0000-0002-1374-7854

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo define optimal parameters for the evaluation of vessel visibility in intracranial stents (ICS) and flow diverters (FD) using photon-counting detector computed tomography angiography (PCD-CTA) with spectral reconstructions.

methodsWe retrospectively analyzed consecutive patients with implanted ICS or FD, who received a PCD-CTA between April 2023 and March 2024. Polyenergetic, virtual monoenergetic, pure lumen, and iodine reconstructions with different keV levels (40, 60, and 80) and reconstruction kernels (body vascular [Bv]48, Bv56, Bv64, Bv72, and Bv76) were evaluated by two radiologists with regions of interests and Likert scales. Reconstructions were compared in descriptive analysis.

resultsIn total, twelve patients with nine FDs and six ICSs were analyzed. In terms of quantitative image quality, sharper kernels as Bv64 and Bv72 yielded increased image noise and decreased signal-to-noise and contrast-to-noise ratios compared to the smoothest kernel Bv48 (p = 0.001). Among the different keV levels and kernels, readers selected the 40 keV level (p = 0.001) and sharper kernels (in the majority of cases Bv72) as the best to visualize the in-stent vessel lumen. Assessing the different spectral reconstructions virtual monoenergetic and iodine reconstructions proved to be best to evaluate in-stent vessel lumen (p = 0.001).

conclusionPCD-CTA and spectral reconstructions with sharper reconstruction kernels and a low keV level of 40 seem to be beneficial to achieve optimal image quality for the evaluation of ICS and FD. Iodine and virtual monoenergetic reconstructions were superior to pure lumen and polyenergetic reconstructions to evaluate in-stent vessel lumen. RELEVANCE STATEMENT: PCD-CTA offers the opportunity to reduce the need for invasive angiography serving as follow-up examination after intracranial stent (ICS) or flow diverter (FD) implantation. KEY POINTS: Neuroimaging of intracranial vessels with implanted stents and flow diverters is limited by artifacts. Twelve patients with nine flow diverters and six intracranial stents underwent photon-counting detector computed tomography angiography (PCD-CTA). In-stent vessel lumen visibility improved using sharp reconstruction kernels and a low keV level. Virtual monoenergetic and iodine reconstructions were best to evaluate in-stent vessel lumen.

Indexed as

Cerebral AngiographyComputed Tomography AngiographyStentsAdultAgedFemaleHumansMaleMiddle AgedPhotonsRetrospective StudiesSignal-To-Noise RatioArtifactsCerebral arterial diseasesComputed tomography angiographyIntracranial aneurysmStents

Identifiers

PMID39881008
PMCPMC11780015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.