Evidence map›Paper›PMID 39880821›Full record

ArticleEpidemiology and psychiatric sciences2025

Is there a mental health diagnostic crisis in primary care? Current research practices in global mental health cannot answer that question.

Brandon A Kohrt, Dristy Gurung, Ritika Singh, Sauharda Rai, Mani Neupane, Elizabeth L Turner, Alyssa Platt, Shifeng Sun, Kamal Gautam, Nagendra P Luitel and 1 more

Abstract read
In one paragraph

Article in Epidemiology and psychiatric sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Brandon A KohrtCenter for Global Mental Health Equity, Department of Psychiatry and Behavioral Health, George Washington University, Washington, DC, USA.ORCID https://orcid.org/0000-0002-3829-4820
Dristy GurungResearch Department, Transcultural Psychosocial Organization Nepal (TPO Nepal), Kathmandu, Nepal.ORCID https://orcid.org/0000-0003-1839-9382
Ritika SinghCenter for Global Mental Health Equity, Department of Psychiatry and Behavioral Health, George Washington University, Washington, DC, USA.ORCID https://orcid.org/0000-0001-5039-4835
Sauharda RaiCenter for Global Mental Health Equity, Department of Psychiatry and Behavioral Health, George Washington University, Washington, DC, USA.ORCID https://orcid.org/0000-0002-9393-1466
Mani NeupaneResearch Department, Transcultural Psychosocial Organization Nepal (TPO Nepal), Kathmandu, Nepal.ORCID https://orcid.org/0000-0002-7383-1089
Elizabeth L TurnerDepartment of Biostatistics and Bioinformatics and Duke Global Health Institute, Duke University, DurhamNC, USA.ORCID https://orcid.org/0000-0002-7638-5942
Alyssa PlattDepartment of Biostatistics and Bioinformatics and Duke Global Health Institute, Duke University, DurhamNC, USA.
Shifeng SunDepartment of Biostatistics and Bioinformatics and Duke Global Health Institute, Duke University, DurhamNC, USA.
Kamal GautamCenter for Global Mental Health Equity, Department of Psychiatry and Behavioral Health, George Washington University, Washington, DC, USA.ORCID https://orcid.org/0000-0001-9401-9359
Nagendra P LuitelResearch Department, Transcultural Psychosocial Organization Nepal (TPO Nepal), Kathmandu, Nepal.ORCID https://orcid.org/0000-0002-8291-0205
Mark J D JordansHealth Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, Center for Global Mental Health, King's College London, London, UK.ORCID https://orcid.org/0000-0001-5925-8039

Funding

RESHAPE Diversity SupplementR01MH120649 · NIMH · GEORGE WASHINGTON UNIVERSITY · PI KOHRT, BRANDON ALAN · 2019 to 2023
$3.5M
NIMH NIH HHS R01 MH120649
6 · The paper itself

Abstract

In low- and middle-income countries, fewer than 1 in 10 people with mental health conditions are estimated to be accurately diagnosed in primary care. This is despite more than 90 countries providing mental health training for primary healthcare workers in the past two decades. The lack of accurate diagnoses is a major bottleneck to reducing the global mental health treatment gap. In this commentary, we argue that current research practices are insufficient to generate the evidence needed to improve diagnostic accuracy. Research studies commonly determine accurate diagnosis by relying on self-report tools such as the Patient Health Questionnaire-9. This is problematic because self-report tools often overestimate prevalence, primarily due to their high rates of false positives. Moreover, nearly all studies on detection focus solely on depression, not taking into account the spectrum of conditions on which primary healthcare workers are being trained. Single condition self-report tools fail to discriminate among different types of mental health conditions, leading to a heterogeneous group of conditions masked under a single scale. As an alternative path forward, we propose improving research on diagnostic accuracy to better evaluate the reach of mental health service delivery in primary care. We recommend evaluating multiple conditions, statistically adjusting prevalence estimates generated from self-report tools, and consistently using structured clinical interviews as a gold standard. We propose clinically meaningful detection as 'good-enough' diagnoses incorporating multiple conditions accounting for context, health system and types of interventions available. Clinically meaningful identification can be operationalized differently across settings based on what level of diagnostic specificity is needed to select from available treatments. Rethinking research strategies to evaluate accuracy of diagnosis is vital to improve training, supervision and delivery of mental health services around the world.

Indexed as

Mental DisordersMental HealthMental Health ServicesPrimary Health CareGlobal HealthHumansPrevalenceSelf Reportdepressiondeveloping countriesdiagnosisglobal healthprimary carepsychiatric status rating scalespsychosisscreening

Identifiers

PMID39880821
PMCPMC11822449

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.