Evidence map›Paper›PMID 39880440›Full record

ArticleBMJ open2025

Epidemiological analysis of reported acute glyphosate poisoning in Malaysia: identifying risk factors and high-risk groups (2006-2023).

Mohd Fadhli Razali, Nurul Iffah Amir Shah Ruddin, Noor Afiza Abdul Rani, Fahim Mohamed, Nurul Izzah Ahmad, Yin-Hui Leong

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Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Mohd Fadhli RazaliNational Poison Centre, Universiti Sains Malaysia, Georgetown, Penang, Malaysia.
Nurul Iffah Amir Shah RuddinNational Poison Centre, Universiti Sains Malaysia, Georgetown, Penang, Malaysia.
Noor Afiza Abdul RaniNational Poison Centre, Universiti Sains Malaysia, Georgetown, Penang, Malaysia.
Fahim MohamedFaculty of Medicine, South Asian Clinical Toxicology Research Collaboration (SACTRC), Peradeniya, Sri Lanka.
Nurul Izzah AhmadInstitute for Medical Research, National Institute of Health, Shah Alam, Selangor, Malaysia.
Yin-Hui LeongNational Poison Centre, Universiti Sains Malaysia, Georgetown, Penang, Malaysia yinhui_leong@yahoo.com.ORCID http://orcid.org/0000-0001-6767-6425

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveGlyphosate is widely used in Malaysian agriculture but poses a significant under-reported public health concern due to poisoning. This paper aims to study the epidemiology of glyphosate poisoning in Malaysia, assessing severity, identifying risk factors, and high-risk groups.

settingAll glyphosate-related data of the Malaysia National Poison Centre from 2006 to 2023.

participantsTelephone inquiries of incidents involving glyphosate made by healthcare professionals across Malaysia. Information received was recorded according to WHO guidelines. OUTCOMES: The outcome is to provide an overview of national glyphosate poisoning epidemiology, including identifying risk factors and high-risk groups to strategise appropriate measures.

resultsA total of 4548 glyphosate poisoning cases were reported, with males comprising 67.3% of cases. The most affected age groups were 21-30 years (25.5%) and 31-40 years (23.5%). Ingestion was the primary exposure route (93.0%). Intentional poisonings, mainly suicides, accounted for 68.4% (n=3078) of cases. Among the 1420 unintentional cases, 78.2% resulted from ingestion exposures. The incidence rate declined from 1.17 per 100 000 in 2011 to 0.61 in 2023. Significant associations were found between intentional ingestion and sociodemographic factors. From 2013 to 2023, 73.7% of cases were minor, 11.5% moderate, 0.8% severe and 0.1% fatal.

conclusionsIn Malaysia, the reported intentional glyphosate poisoning most commonly affects young adults, resulting in generally minor to moderate symptoms. The study highlights the need for stricter regulations on glyphosate use and improved mental health support, to mitigate poisoning risks. Continued surveillance and public education are essential to address this public health issue.

Indexed as

GlycineHerbicidesPoisoningAdolescentAdultAgedChildChild, PreschoolFemaleGlyphosateHumansIncidenceInfantMalaysiaMaleMiddle AgedGlycineGlyphosateHerbicidesEPIDEMIOLOGYRetrospective StudiesRisk Factors

Identifiers

PMID39880440
PMCPMC11781103

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