Evidence map›Paper›PMID 39880329›Full record

ArticleContemporary clinical trials2025

Using augmented reality to deliver cue exposure treatment for smoking cessation: App usability findings and protocol for a randomized controlled trial.

Ranjita Poudel, Skye O Dougan, Helen Yates, Leslie Sawyer, Ursula Martinez, Karen O Brandon, Steven K Sutton, Damon J Vidrine, Lee M Ritterband, Kara P Wiseman and 7 more

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Contemporary clinical trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06088498 (Augmented Reality as an Adjunct to Quitline Counseling for Smoking Cessation), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06088498 phase2recruitingnot on this map

Augmented Reality as an Adjunct to Quitline Counseling for Smoking Cessation

TypeinterventionalSponsorH. Lee Moffitt Cancer Center and Research InstituteRan2024 to 2027Enrolled3,600ConditionsSmokingArmsUpdating Existing Smartphone App, Quitline Services, Quitline Services and Smartphone App
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Ranjita PoudelDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.
Skye O DouganDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.
Helen YatesDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.
Leslie SawyerDepartment of Psychology, University of South Florida, Tampa, FL, USA.
Ursula MartinezDepartment of Family and Preventive Medicine, University of Utah, Salt Lake City, UT, USA.
Karen O BrandonDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.
Steven K SuttonDepartment of Psychology, University of South Florida, Tampa, FL, USA; Department of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, FL, USA; Department of Oncological Sciences, University of South Florida, Tampa, FL, USA.
Damon J VidrineDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA; Department of Oncological Sciences, University of South Florida, Tampa, FL, USA.
Lee M RitterbandCenter for Behavioral Health and Technology, Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA, USA.
Kara P WisemanDepartment of Public Health Sciences, School of Medicine, University of Virginia, Charlottesville, VA, USA.
Katrina A VickermanCenter for Wellbeing Research, RVO Health, Fort Mill, SC, USA.
Kea TurnerDivision of Health Systems, Policy, and Innovation, University of North Carolina at Chapel Hill School of Nursing, Chapel Hill, NC, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Margaret M ByrneDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.
Min-Jeong YangInstitute for Nicotine and Tobacco Studies, Rutgers Biomedical and Health Sciences (Rutgers Health), Rutgers, The State University of New Jersey, New Brunswick, NJ, USA; Department of Health Behavior, Society, and Policy, School of Public Health, Rutgers, The State University of New Jersey, Piscataway, NJ, USA.
Marilyn HortaDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.
Thomas H BrandonDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA; Department of Psychology, University of South Florida, Tampa, FL, USA.
Christine VinciDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA; Department of Psychology, University of South Florida, Tampa, FL, USA; Department of Oncological Sciences, University of South Florida, Tampa, FL, USA. Electronic address: christine.vinci@moffitt.org.

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI John L. Cleveland · 1998 to 2026
$93.5M
Augmented Reality as an Adjunct to Quitline Counseling for Smoking CessationR01DA055298 · NIDA · H. LEE MOFFITT CANCER CTR & RES INST · PI VINCI, CHRISTINE · 2022 to 2025
$3.0M
Behavioral Oncology Education & Career DevelopmentT32CA090314 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI Vani N Simmons, SUSAN T VADAPARAMPIL · 2019 to 2026
$2.9M
Enhancing motivation to quit smoking via self-help intervention targeted to cancer type: A pilot RCTK22CA276255 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Ursula Martinez Pradeda · 2024 to 2026
$583k
Mindfulness-based ecological momentary intervention for smoking cessation among cancer survivorsR00CA271040 · NCI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Min-Jeong Yang · 2025 to 2026
$461k
Mindfulness-based ecological momentary intervention for smoking cessation among cancer survivorsK99CA271040 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI YANG, MIN-JEONG · 2023 to 2024
$238k
NCI NIH HHS K22 CA276255NCI NIH HHS K99 CA271040NCI NIH HHS P30 CA076292NCI NIH HHS R00 CA271040NCI NIH HHS T32 CA090314NIDA NIH HHS R01 DA055298
6 · The paper itself

Abstract

backgroundAugmented Reality (AR) is a rapidly developing technology with potential utility for treating addictive behaviors, including tobacco smoking. AR inserts digital images into a natural real-time scene as viewed on a smartphone or other video devices. With respect to smoking cessation, AR can place virtual smoking cues (i.e., smoking "triggers") within an individual's natural smoking environment. Repeated exposure to these cues could enhance smoking cessation through Pavlovian extinction processes.

methodIn a usability study (N = 10), we evaluated the acceptability of a smoking cessation AR app to inform modifications to the app prior to an upcoming randomized controlled trial (RCT). For the subsequent RCT, individuals who enroll in a state tobacco quitline will be referred to the study and, if eligible and consented, randomized to use the app with AR features or without AR features (control) for 5 weeks. The efficacy of the AR features to enhance smoking cessation in the context of concurrent quitline treatment will be evaluated with the primary outcome of self-reported 7-day point-prevalence cigarette abstinence at 6 months post-enrollment. Implementation will be evaluated via incremental cost-effectiveness analyses and interviews with participants, quitline staff, and app coaches.

conclusionsInterventions utilizing emerging mobile technologies such as AR have the potential, compared to traditional therapies, to improve both reach and efficacy by administering therapeutic elements in users' natural environments. Our AR app will target tobacco smoking, but the approach could be used to deliver exposure therapies for other addictive behaviors, as well as anxiety disorders. CLINICAL

trial registrationNCT06088498.

Indexed as

Augmented RealityCuesImplosive TherapyMobile ApplicationsSmoking CessationAdultCost-Benefit AnalysisFemaleHumansMaleRandomized Controlled Trials as TopicAugmented realityCue exposure therapymHealthSmartphone applicationSmoking cessation

Identifiers

PMID39880329
PMCPMC12149911

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.