Evidence map›Paper›PMID 39880212›Full record

Trial reportInternational journal of psychophysiology : official journal of the International Organization of Psychophysiology2025

Interrupting sitting with moderate-intensity physical activity breaks improves cognitive processing speed in adults with overweight and obesity: Findings from the SITLess pilot randomized crossover trial.

Dominika M Pindus, Kathryn M Lloyd, Tomasz S Ligeza, A Askow, C McKenna, Neha Bashir, Hannah Martin, Flor B Quiroz, Bryan Montero Herrera, Corrinne Cannavale and 10 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of psychophysiology : official journal of the International Organization of Psychophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Effect of breaking up prolonged sitting with physical activity on executive function: a three-level meta-analysis.The international journal of behavioral nutrition and physical activity · 2026
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Dominika M PindusDepartment of Health and Kinesiology, the University of Illinois Urbana-Champaign, Urbana, IL, USA; Neuroscience Program, University of Illinois at Urbana-Champaign, Urbana, IL, USA; Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, USA. Electronic address: pindus@illinois.edu.
Kathryn M LloydDepartment of Psychology, Northeastern University, Boston, MA, USA. Electronic address: mcdonald.kath@northeastern.edu.
Tomasz S LigezaInsitute of Psychology, Jagiellonian University, Krakow, Poland. Electronic address: tomasz.ligeza@uj.edu.pl.
A AskowDepartment of Health and Kinesiology, the University of Illinois Urbana-Champaign, Urbana, IL, USA. Electronic address: askow2@illinois.edu.
C McKennaDivision of Nutritional Sciences, University of Illinois at Urbana- Champaign, Urbana, IL, USA. Electronic address: colleen.mckenna@cuanschutz.edu.
Neha BashirDepartment of Health and Kinesiology, the University of Illinois Urbana-Champaign, Urbana, IL, USA; The School of Cellular and Molecular Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA. Electronic address: nbash2@illinois.edu.
Hannah MartinDepartment of Health and Kinesiology, the University of Illinois Urbana-Champaign, Urbana, IL, USA; The School of Cellular and Molecular Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Flor B QuirozDepartment of Health and Kinesiology, the University of Illinois Urbana-Champaign, Urbana, IL, USA; Department of Psychology, University of Illinois at Urbana-Champaign, USA. Electronic address: fquir3@illinois.edu.
Bryan Montero HerreraDepartment of Health and Kinesiology, the University of Illinois Urbana-Champaign, Urbana, IL, USA; Department of Kinesiology, University of North Carolina at Greensboro, USA.
Corrinne CannavaleCarl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA. Electronic address: cannava2@illinois.edu.
Jin KuangDepartment of Health and Kinesiology, the University of Illinois Urbana-Champaign, Urbana, IL, USA; Body-Brain-Mind Laboratory, School of Psychology, Shenzhen University, Shenzhen 518060, China.
Qian YuBody-Brain-Mind Laboratory, School of Psychology, Shenzhen University, Shenzhen 518060, China.
Maciej KosCenter for Cognitive & Brain Health, Northeastern University, Boston, MA, USA. Electronic address: mkos@ccs.neu.edu.
Candace S BrownDepartment of Epidemiology and Community Health, University of North Carolina at Charlotte, Charlotte, NC, USA. Electronic address: cbrow342@charlotte.edu.
Tayla von AshDepartment of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI, USA. Electronic address: tayla_ash@brown.edu.
Liye ZouBody-Brain-Mind Laboratory, School of Psychology, Shenzhen University, Shenzhen 518060, China.
Nicholas A BurdDepartment of Health and Kinesiology, the University of Illinois Urbana-Champaign, Urbana, IL, USA; Division of Nutritional Sciences, University of Illinois at Urbana- Champaign, Urbana, IL, USA. Electronic address: naburd@illinois.edu.
Naiman A KhanDepartment of Health and Kinesiology, the University of Illinois Urbana-Champaign, Urbana, IL, USA; Neuroscience Program, University of Illinois at Urbana-Champaign, Urbana, IL, USA; Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, USA; Division of Nutritional Sciences, University of Illinois at Urbana- Champaign, Urbana, IL, USA. Electronic address: nkahn2@illinois.edu.
Arthur F KramerBeckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, USA; Center for Cognitive & Brain Health, Northeastern University, Boston, MA, USA. Electronic address: a.kramer@northeastern.edu.
Charles H HillmanDepartment of Psychology, Northeastern University, Boston, MA, USA; Center for Cognitive & Brain Health, Northeastern University, Boston, MA, USA; Department of Physical Therapy, Movement, & Rehabilitation Sciences, Northeastern University, Boston, MA, USA. Electronic address: c.hillman@northeastern.edu.

Funding

Unobtrusive and continuous monitoring of cognitive changes using smartphonesK00AG068503 · NIA · NORTHEASTERN UNIVERSITY · PI Maciej Rafal Kos · 2024 to 2026
$235k
NIA NIH HHS K00 AG068503
6 · The paper itself

Abstract

introductionProlonged sitting can acutely reduce working memory (WM) in individuals with overweight and obesity (OW/OB) who show executive function deficits. Interrupting prolonged sitting with brief PA bouts may counter these effects. However, the benefits of such interventions on behavioral and neuroelectric indices of WM and whether neurocognitive responses are associated with postprandial glycemic responses in young and middle-aged adults with OW/OB remain unknown. To address this gap, this study examined the acute effects of interrupting three-hour prolonged sitting every 30 min with 3.5-min moderate-intensity physical activity (MPA) bouts (MPA + SIT condition) relative to sedentary social interaction condition (SOC + SIT) on behavioral measures of WM and the P3b component of event-related potentials (ERP) in young and middle-aged adults with OW/OB.

methodNineteen adults with OW/OB (63 % females; 29.9 ± 7.5 years; BMI = 30.0 ± 3.64 kg*m

resultsNo significant intervention effects on glucose were noted (p = 0.74). Compared to SOC + SIT, MPA + SIT resulted in shorter 1-back target P3b latency (F(1, 17.0) = 5.14, p = 0.037; M

conclusionInterrupting sitting with short MPA bouts can enhance some aspects of cognitive processing in adults with OW/OB. Future studies are needed to better understand behavioral responses to interrupting prolonged sitting with MPA bouts and the underlying mechanisms.

Indexed as

Event-Related Potentials, P300Evoked PotentialsExecutive FunctionExerciseMemory, Short-TermObesityOverweightSedentary BehaviorSitting PositionAdultCross-Over StudiesFemaleHumansMaleMiddle AgedPilot ProjectsEvent-related brain potentialsGlycemic responseObesityPhysical activityProlonged sittingRandomized controlled trialWorking memory

Identifiers

PMID39880212
PMCPMC13225338

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.