Evidence map›Paper›PMID 39879613›Full record

Trial reportJournal of medical Internet research2025

Real-Time fMRI Neurofeedback Modulation of Dopaminergic Midbrain Activity in Young Adults With Elevated Internet Gaming Disorder Risk: Randomized Controlled Trial.

Anqi Gu, Cheng Lam Chan, Xiaolei Xu, Joseph P Dexter, Benjamin Becker, Zhiying Zhao

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of medical Internet research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06063642 (Real-time Functional Magnetic Resonance Imaging Neurofeedback Treatment for Young Adults With Internet Gaming Addiction), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06063642 nacompletednot on this map

Real-time Functional Magnetic Resonance Imaging Neurofeedback Treatment for Young Adults With Internet Gaming Addiction

TypeinterventionalSponsorUniversity of MacauRan2023 to 2024Enrolled20ConditionsInternet Gaming DisorderArmsNeurofeedback training, Sham feedback training
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anqi GuCentre for Cognitive and Brain Sciences, Institute of Collaborative Innovation, University of Macau, Macau, China.ORCID https://orcid.org/0009-0007-5771-330X
Cheng Lam ChanCentre for Cognitive and Brain Sciences, Institute of Collaborative Innovation, University of Macau, Macau, China.ORCID https://orcid.org/0009-0006-4430-4577
Xiaolei XuSchool of Psychology, Shandong Normal University, Jinan, China.ORCID https://orcid.org/0000-0003-3817-0411
Joseph P DexterCentre for Data Science, Institute of Collaborative Innovation, University of Macau, Macau, China.ORCID https://orcid.org/0000-0001-8524-5792
Benjamin BeckerThe State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Hong Kong, China.ORCID https://orcid.org/0000-0002-9014-9671
Zhiying ZhaoCentre for Cognitive and Brain Sciences, Institute of Collaborative Innovation, University of Macau, Macau, China.ORCID https://orcid.org/0000-0002-0369-1308

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study provides preliminary evidence for real-time functional magnetic resonance imaging neurofeedback (rt-fMRI NF) as a potential intervention approach for internet gaming disorder (IGD). In a preregistered, randomized, single-blind trial, young individuals with elevated IGD risk were trained to downregulate gaming addiction-related brain activity. We show that, after 2 sessions of neurofeedback training, participants successfully downregulated their brain responses to gaming cues, suggesting the therapeutic potential of rt-fMRI NF for IGD (Trial Registration: ClinicalTrials.gov NCT06063642; https://clinicaltrials.gov/study/NCT06063642).

Indexed as

Behavior, AddictiveInternet Addiction DisorderMagnetic Resonance ImagingMesencephalonNeurofeedbackVideo GamesAdolescentAdultFemaleHumansMaleSingle-Blind MethodYoung Adultcravinginternet gaming disorderreal-time functional magnetic resonance imaging neurofeedbackreward processingventral tegmental area

Identifiers

PMID39879613
PMCPMC11822309

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.