Evidence map›Paper›PMID 39879556›Full record

ReviewAnnual review of clinical psychology2025

Treating Opioid Use Disorder and Opioid Withdrawal in the Context of Fentanyl.

Suky Martinez, Jennifer D Ellis, Cecilia L Bergeria, Andrew S Huhn, Kelly E Dunn

Abstract readReview
In one paragraph

Review in Annual review of clinical psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Acute fentanyl induces opposing directions of changes in tonic and phasic dopamine release patterns and impairs Pavlovian task performance.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  3. Article
  4. Article
  5. Molecular mechanism of allosteric modulation of opioid receptors.Signal transduction and targeted therapy · 2026
    Article
  6. [Psychiatry as clinical neuroscience].Revista medica del Instituto Mexicano del Seguro Social · 2026
    Review
  7. Article
  8. Reliable variability in subjective responses to parenteral hydromorphone administration: empirical confirmation of an opioid non-responder phenotype.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Suky MartinezBehavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; email: smart209@jh.edu.
Jennifer D EllisBehavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; email: smart209@jh.edu.
Cecilia L BergeriaBehavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; email: smart209@jh.edu.
Andrew S HuhnBehavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; email: smart209@jh.edu.
Kelly E DunnBehavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; email: smart209@jh.edu.

Funding

Evaluating Suvorexant for Sleep Disturbance in Opioid Use DisorderUH3DA048734 · NIDA · JOHNS HOPKINS UNIVERSITY · PI DUNN, KELLY E, HUHN, ANDREW S · 2021 to 2021
$3.6M
Assessing a Clinically-meaningful Opioid Withdrawal PhenotypeR01DA052937 · NIDA · UNIVERSITY OF MARYLAND BALTIMORE · PI DUNN, KELLY E · 2021 to 2025
$3.3M
Natural Language Processing Phenotyping of Spirituality and Resilience Among Individuals with Opioid Use DisorderK08DA058057 · NIDA · JOHNS HOPKINS UNIVERSITY · PI Suky Martinez · 2024 to 2026
$655k
NIDA NIH HHS K08 DA058057NIDA NIH HHS R01 DA052937NIDA NIH HHS UH3 DA048734
6 · The paper itself

Abstract

The opioid crisis, driven by illicitly manufactured fentanyl, presents significant challenges in treating opioid use disorder (OUD) and opioid withdrawal syndrome. Fentanyl is uniquely lethal due to its rapid onset and respiratory depressant effects, driving the surge in overdose deaths. This review examines the limitations of traditional diagnostic criteria like those of the

Indexed as

Analgesics, OpioidFentanylOpiate Substitution TreatmentOpioid-Related DisordersSubstance Withdrawal SyndromeHumansAnalgesics, OpioidFentanylfentanylheterogeneityHiTOPmethadoneMOUDopioid use disorderopioid withdrawal syndrome

Identifiers

PMID39879556
PMCPMC13147498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.