Observational studyArquivos brasileiros de oftalmologia2025
Estimating the volume of the vitrectomized space using axial length: a guideline.
Observational study in Arquivos brasileiros de oftalmologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Urea nitrogen levels in postmortem serum, vitreous humor, and cerebrospinal fluid.International journal of legal medicine · 2026Article
- Real-World Validation of the VIVEX Formula for Vitreous Volume Estimation in Vitreoretinal Surgery: A First Clinical Case Series.Ophthalmology and therapy · 2026Article
- Association between axial length and perfluoropropane gas duration after pars plana vitrectomy with fixed-volume pure gas injection.Arquivos brasileiros de oftalmologia · 2025Article
- Dose adjustment of intravitreal medications and gases according to axial length and vitreous cavity volume.Arquivos brasileiros de oftalmologia · 2025Article
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7 authors.
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Abstract
purposeThe volume of the vitreous chamber varies with the size of the eye. The space created in the vitreous cavity by a vitrectomy is called the vitrectomized space. The volume of the vitrectomized space is strongly correlated with the axial length of the eye. This study aims to present guidelines for estimating the using participants stratified by axial length, sex, and history of cataract surgery.
methodsThis retrospective, observational, cross-sectional study included 144 randomly selected participants who underwent vitrectomies between 2013 and 2023. Before surgery, the axial lengths of participants' eyes were measured using optical biometrics. The axial lengths of the eyes in our sample were between 20-32 mm. In all cases, a complete vitrectomy was performed, followed by complete fluid-air exchange and injection of a balanced saline solution. The volume infused was recorded.
resultsThe median (interquartile range; range) volume of the vitrectomized space was 6.1 (3.8; 3.1-11.3) mL in men and 6.1 (3.3; 3.2-11.2) mL in women (p = 0.811). The median volume of the vitrectomized space was 5.9 (3.6; 3.1-11.2) mL in patients with phakic lenses and 6.25 (3.6; 3.3-11.3) mL in those with pseudophakic lenses (p=0.533). A positive correlation was found between the axial length and the volume of the vitrectomized space in this sample (r=0.968; p<0.001). In a cubic polynomial regression, the coefficient of determination was 0.948. Similar results were observed in both sexes and in both phakic and pseudophakic patients. The estimated cubic polynomial regression equation for this sample was VVS = 0.000589052857847605 × AL 3 - 0.025114926401582700 × AL 2 + 0.685961117595624000 × AL - 5.088226672620790000.
conclusionWe developed this axial length estimation of the volume of vitrectomized space as a guideline for the determination of vitrectomized space volume using axial length.
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