Evidence map›Paper›PMID 39879174›Full record

ArticlePloS one2025

A simple tool to evaluate the effectiveness of HIV care for settings with gaps in data availability (ESTIHIV).

Dorthe Raben, Marie L Jakobsen, Jamina Trajanovska, Justyna Kowalska, Anna Vassilenko, Snezana Dragas, Arjan Harxhi, Gordana Dragovic, Nadine J Jaschinski, Bastian Neesgaard and 8 more

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Dorthe RabenCHIP, Rigshospitalet, University of Copenhagen, Denmark.
Marie L JakobsenCHIP, Rigshospitalet, University of Copenhagen, Denmark.ORCID 0000-0002-6436-8993
Jamina TrajanovskaUniversity Clinic for Infectious Diseases & Febrile Conditions, Skopje, North Macedonia.
Justyna KowalskaMedical University of Warsaw, Warsaw, Poland.
Anna VassilenkoBelarusian State Medical University, Minsk, Belarus.
Snezana DragasClinical Center of Montenegro, Podgorica, Montenegro.
Arjan HarxhiFaculty of Medicine, Medical University of Tirana, Albania.
Gordana DragovicUniversity of Belgrade Faculty of Medicine, Department of Pharmacology, Clinical Pharmacology and Toxicology, Belgrade, Serbia.ORCID 0000-0002-0438-0309
Nadine J JaschinskiCHIP, Rigshospitalet, University of Copenhagen, Denmark.
Bastian NeesgaardCHIP, Rigshospitalet, University of Copenhagen, Denmark.
Klaus Hjorth-LarsenCHIP, Rigshospitalet, University of Copenhagen, Denmark.
Harmony GargesViiV. Healthcare, Research Triangle Park, North Carolina, United States of America.
Joel GallantGilead Sciences, Foster City, California, United States of America.
Jens D LundgrenCHIP, Rigshospitalet, University of Copenhagen, Denmark.
Andrew PhilipsUniversity College London, London, United Kingdom.
Valentina CambianoUniversity College London, London, United Kingdom.
Yazdan YazdanpanahUniversité Paris Diderot, Sorbonne Paris Cité, Paris, France.
Amanda MocroftCHIP, Rigshospitalet, University of Copenhagen, Denmark.

Funding

The Asia-Pacific HIV Research CollaborationU01AI069907 · NIAID · FOUNDATION FOR AIDS RESEARCH · PI ANNETTE H SOHN · 2006 to 2026
$44.8M
NIAID NIH HHS U01 AI069907
6 · The paper itself

Abstract

Many HIV clinics with poor IT-infrastructure are unable to report data on individuals in care with HIV, on antiretroviral treatment (ART) and virologically suppressed (VS), with the aim of monitoring the HIV Continuum of Care to estimate efficacy of HIV treatment programmes. We developed an estimation-tool, ESTIHIV, and determined the minimal data required for a random sample, to produce representative estimates, with a specified level of precision, of people with HIV on ART and VS. For proof of concept, 8852 HIV positive persons from seven clinics in seven different countries, with a follow-up visit during 2017, were included. Of those, 93.8% were on ART (95% CI 93.3-94.2) and 76.7% were VS (95% CI 75.8-77.6). In 2022, we tested the tool in the RESPOND Cohort for all countries with more than 100 participants under follow-up in 2019. We included 26,426 HIV positive persons from clinics in 27 countries, 97.8% (95% CI 97.6-98.0) were on ART and 91.5% were VS (95% CI 91.2-91.8%). There was good agreement between the RESPOND country estimates of ART and VS and the estimations using a random sample calculated in ESTIHIV. With ESTIHIV, clinics can produce a reliable estimate in figures for reporting and for monitoring the effectiveness of care in their clinics.

Indexed as

Anti-HIV AgentsHIV InfectionsAdultFemaleHumansMaleMiddle AgedAnti-HIV Agents

Identifiers

PMID39879174
PMCPMC11778770

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.