Evidence map›Paper›PMID 39878901›Full record

ReviewApplied microbiology and biotechnology2025

Eco-friendly zinc oxide nanoparticle biosynthesis powered by probiotic bacteria.

Ahmed Issa Al-Tameemi, Mas Jaffri Masarudin, Raha Abdul Rahim, Rachel Mizzi, Verlaine J Timms, Nurulfiza Mat Isa, Brett A Neilan

Abstract readReview
In one paragraph

Review in Applied microbiology and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Phyto-Mediated Zinc Oxide Nanoparticles fromLife (Basel, Switzerland) · 2025
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ahmed Issa Al-TameemiSchool of Environmental and Life Sciences, The University of Newcastle, Callaghan, NSW, 2308, Australia.
Mas Jaffri MasarudinDepartment of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
Raha Abdul RahimDepartment of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
Rachel MizziSchool of Environmental and Life Sciences, The University of Newcastle, Callaghan, NSW, 2308, Australia.
Verlaine J TimmsSchool of Environmental and Life Sciences, The University of Newcastle, Callaghan, NSW, 2308, Australia.
Nurulfiza Mat IsaDepartment of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia. nurulfiza@upm.edu.my.
Brett A NeilanSchool of Environmental and Life Sciences, The University of Newcastle, Callaghan, NSW, 2308, Australia. brett.neilan@newcastle.edu.au.ORCID http://orcid.org/0000-0001-6113-772X

Funding

6369101 CE200100029
6 · The paper itself

Abstract

The rapid advancement of nanotechnology, particularly in the realm of pharmaceutical sciences, has significantly transformed the potential for treating life-threatening diseases. A pivotal aspect of this evolution is the emergence of "green nanotechnology," which emphasizes the environmentally sustainable synthesis of raw materials through biological processes. This review focuses on the biological synthesis and application of zinc oxide (ZnO) nanoparticles (NPs) from probiotic bacteria, particularly those sourced from wastewater. Microorganisms from wastewater tolerate harmful elements and enzymatically convert toxic heavy metals into eco-friendly materials. These probiotic bacteria are instrumental in the synthesis of ZnO NPs and exhibit remarkable antimicrobial properties with diverse industrial applications. As the challenge of drug-resistant pathogens escalates, innovative strategies for combating microbial infections are essential. This review explores the intersection of nanotechnology, microbiology, and antibacterial resistance, highlighting the importance of selecting suitable probiotic bacteria for synthesizing ZnO NPs with potent antibacterial activity. Additionally, the review addresses the biofunctionalization of NPs and their applications in environmental remediation and therapeutic innovations, including wound healing, antibacterial, and anticancer treatments. Eco-friendly NP synthesis relies on the identification of these suitable microbial "nano-factories." Targeting probiotic bacteria from wastewater can uncover new microbial NP synthesis capabilities, advancing environmentally friendly NP production methods. KEY POINTS: • Innovative strategies are needed to combat drug-resistant pathogens like MRSA. • Wastewater-derived probiotic bacteria are an eco-friendly method for ZnO synthesis. • ZnO NPs show significant antimicrobial activity against various pathogens.

Indexed as

BacteriaMetal NanoparticlesNanoparticlesProbioticsZinc OxideAnti-Bacterial AgentsGreen Chemistry TechnologyHumansNanotechnologyWastewaterAnti-Bacterial AgentsWastewaterZinc OxideAntimicrobial activityBiosynthesisProbiotic bacteriaZnO NPs

Identifiers

PMID39878901
PMCPMC11779794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.