Evidence map›Paper›PMID 39878900›Full record

ArticleHuman cell2025

Establishment of a human ovarian endometrioid carcinoma cell line by constitutive expression of cyclin-dependent kinase 4, cyclin D1 and telomerase reverse transcriptase.

Hitomi Hoshino, Tomoya O Akama, Daisuke Inoue, Suzuko Moritani, Shohei Shigeto, Kazuyuki Matsuda, Hisato Yoshida, Natsumi Yonemoto, Mana Fukushima, Yoshio Yoshida and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Human cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hitomi HoshinoDepartment of Tumor Pathology, Faculty of Medical Sciences, University of Fukui, 23-3 Matsuoka-Shimoaizuki, Eiheiji, Fukui, 910-1193, Japan.
Tomoya O AkamaDepartment of Pharmacology, Kansai Medical University, Hirakata, Japan.
Daisuke InoueDepartment of Obstetrics and Gynecology, Faculty of Medical Sciences, University of Fukui, Eiheiji, Japan.
Suzuko MoritaniDivision of Diagnostic Pathology, Shiga University of Medical Science Hospital, Otsu, Japan.
Shohei ShigetoDepartment of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan.
Kazuyuki MatsudaDepartment of Clinical Laboratory Sciences, School of Health Sciences, Shinshu University, Matsumoto, Japan.
Hisato YoshidaDepartment of Tumor Pathology, Faculty of Medical Sciences, University of Fukui, 23-3 Matsuoka-Shimoaizuki, Eiheiji, Fukui, 910-1193, Japan.
Natsumi YonemotoDepartment of Tumor Pathology, Faculty of Medical Sciences, University of Fukui, 23-3 Matsuoka-Shimoaizuki, Eiheiji, Fukui, 910-1193, Japan.
Mana FukushimaDepartment of Tumor Pathology, Faculty of Medical Sciences, University of Fukui, 23-3 Matsuoka-Shimoaizuki, Eiheiji, Fukui, 910-1193, Japan.
Yoshio YoshidaDepartment of Obstetrics and Gynecology, Faculty of Medical Sciences, University of Fukui, Eiheiji, Japan.
Motohiro KobayashiDepartment of Tumor Pathology, Faculty of Medical Sciences, University of Fukui, 23-3 Matsuoka-Shimoaizuki, Eiheiji, Fukui, 910-1193, Japan. motokoba@u-fukui.ac.jp.ORCID http://orcid.org/0000-0002-7607-0801

Funding

Japan Society for the Promotion of Science 21H02702
6 · The paper itself

Abstract

Only a few human ovarian endometrioid carcinoma cell lines are currently available, partly due to the difficulty of establishing cell lines from low-grade cancers. Here, using a cell immortalization strategy consisting of i) inactivation of the p16

Indexed as

Carcinoma, EndometrioidCyclin D1Cyclin-Dependent Kinase 4Gene ExpressionOvarian NeoplasmsTelomeraseCell Line, TumorFemaleHumansMiddle AgedCCND1 protein, humanCDK4 protein, humanCyclin D1Cyclin-Dependent Kinase 4TelomeraseTERT protein, humanCyclin D1Cyclin-dependent kinase 4Endometrioid carcinomaOvaryTelomerase reverse transcriptase

Identifiers

PMID39878900
PMCPMC11779770

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.