Evidence map›Paper›PMID 39878695›Full record

ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2025

Family Size Across the Life Course and Cognitive Decline in Older Mexican Adults.

Joseph Saenz, Nekehia T Quashie, Xing Zhang

Abstract read
In one paragraph

Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joseph SaenzEdson College of Nursing and Health Innovation, Arizona State University, Phoenix, Arizona, USA.ORCID 0000-0002-4200-9615
Nekehia T QuashieDepartment of Public Health, University of Rhode Island, Kingston, Rhode Island, USA.ORCID 0000-0002-2654-1150
Xing ZhangCollege of Health Solutions, Arizona State University, Phoenix, Arizona, USA.ORCID 0000-0002-0796-4940

Funding

The Mexican Health and Aging Study - IIR01AG018016 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Rebeca Wong · 1999 to 2026
$22.6M
Education and the Life-Course Pathways of Cognitive Impairment, Dementia, and Cognitive Decline in the United States and MexicoR00AG058799 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SAENZ, JOSEPH · 2020 to 2022
$745k
NIA NIH HHS R00 AG058799NIA NIH HHS R01 AG018016NIH HHS R00 AG058799
6 · The paper itself

Abstract

objectivesA growing body of research has identified associations between family size and cognition in older adults. These studies largely focus on older adults' own fertility history instead of sibship size, defined as one's number of siblings. Sibship size may affect cognitive development during early childhood, creating differences that may persist into late life. Using a gendered life course framework, this study evaluates how family size across the life course (both sibship size and number of children) relates to cognitive aging among older Mexican adults.

methodsData come from the 2012, 2015, 2018, and 2021 waves of the Mexican Health and Aging Study (n = 14,872 adults age 50+). We use latent growth curve models to evaluate how family size (sibship size and fertility history) relates with levels of latent general cognitive ability and 9-year cognitive decline and variation across gender.

resultsSmall sibship size related to higher levels of cognitive ability among men, but not women. This benefit was somewhat reduced when educational attainment was accounted for. Regarding fertility history, we observed an inverse U-shaped relationship with the level of cognitive ability, regardless of gender, that remained significant even after accounting for sibship size and other confounders. Neither family size measure predicted the rate of cognitive decline. DISCUSSION: This research broadens our understanding of family size and cognition associations in the context of Mexico's changing demographics that challenge the reliance on family support in late life and highlights potential gender differences.

Indexed as

Cognitive AgingCognitive DysfunctionFamily CharacteristicsAgedAged, 80 and overFemaleHumansLongitudinal StudiesMaleMexicoMiddle AgedSex FactorsCognitionFertilityGenderResource dilutionSiblings

Identifiers

PMID39878695
PMCPMC11974380

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.