ArticleEnvironmental health perspectives2025
The Critical Role of Commercial Analytical Reference Standards in the Control of Chemical Risks: The Case of PFAS and Ways Forward.
Article in Environmental health perspectives, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- PFAS: challenges and scientific perspectives in human health risk assessment.Archives of toxicology · 2026Article
- Analytical Tools for Understanding Molecular Level Interactions of Per- and Polyfluoroalkyl Substances (PFAS) with Sorbent Materials.Analytical chemistry · 2026Review
- Navigating per- and polyfluoroalkyl substances in organic waste streams: Sources, challenges and implications for circular economy recycling - A mini-review.Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA · 2026Review
- A Hazard-Based Approach Enables the Efficient Identification of Chemicals of Concern in Plastics.Environmental science & technology · 2025Review
- Application of a Non-targeted Biomonitoring Method to Characterize Occupational Chemical Exposures of Women Nurses Relative to Office Workers.Environmental science & technology · 2025Article
- Invited Perspective: Reference Standards Are Key to Environmental and Human Health Research-The Case of PFAS.Environmental health perspectives · 2025Article
- Comparison of Compound Identification Tools Using Data Dependent and Data Independent High-Resolution Mass Spectrometry Spectra.Metabolites · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVarious countries have instituted risk governance measures to control and minimize the risks of chemicals at the national and international levels. Activities typically include risk assessment based on
objectiveWe outline how current chemical risk governance is hampered by the widespread lack of reference standards to produce the required scientific evidence. We also provide a list of recommendations for controlling chemical risks in the absence of reference standards. DISCUSSION: We use per- and polyfluoroalkyl substances (PFASs), specifically the chemical C6O4 [perfluoro ([5-methoxy-1,3-dioxolan-4-yl]oxy) acetic acid], to illustrate how companies that produce chemicals can prevent access to reference standards. We argue that the very limited availability of reference standards undermines the ability of scientists to produce independent scientific evidence needed for chemical risk governance and, thereby, prevents society from protecting people and the environment against chemical pollution and its harms. Possible ways to improve the situation include
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.