Evidence map›Paper›PMID 39878472›Full record

ReviewJournal of virology2025

Pathogen genomic surveillance and the AI revolution.

Spyros Lytras, Kieran D Lamb, Jumpei Ito, Joe Grove, Ke Yuan, Kei Sato, Joseph Hughes, David L Robertson

Abstract readReview
In one paragraph

Review in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Global Genomic Surveillance.Methods in molecular biology (Clifton, N.J.) · 2027
    Article
  2. Review
  3. Review
  4. Article
  5. China CDC weekly · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Spyros LytrasDivision of Systems Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.ORCID 0000-0003-4202-6682
Kieran D LambMRC-University of Glasgow Centre for Virus Research, Glasgow, Scotland, United Kingdom.ORCID 0000-0002-3011-5189
Jumpei ItoDivision of Systems Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.ORCID 0000-0003-0440-8321
Joe GroveMRC-University of Glasgow Centre for Virus Research, Glasgow, Scotland, United Kingdom.ORCID 0000-0001-5390-7579
Ke YuanSchool of Computing Science, University of Glasgow, Glasgow, Scotland, United Kingdom.ORCID 0000-0002-2318-1460
Kei SatoDivision of Systems Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.ORCID 0000-0003-4431-1380
Joseph HughesMRC-University of Glasgow Centre for Virus Research, Glasgow, Scotland, United Kingdom.ORCID 0000-0003-2556-2563
David L RobertsonMRC-University of Glasgow Centre for Virus Research, Glasgow, Scotland, United Kingdom.ORCID 0000-0001-6338-0221

Funding

Japan Agency for Medical Research and Development (AMED) JP24jf0126002, JP243fa627001, JP243fa727002, JP24fk0108690MEXT | Japan Society for the Promotion of Science (JSPS) JP23K14526MEXT | Japan Society for the Promotion of Science (JSPS) JP24H00607MEXT | JST | Precursory Research for Embryonic Science and Technology (PRESTO) JPMJPR22R1UK Research and Innovation (UKRI) MR/Y004205/1UKRI | Medical Research Council (MRC) MC_UU_12014/12, MC_UU_00034/5,MR/V01157X/1UKRI | Medical Research Council (MRC) MR/N013166/1Wellcome TrustWellcome Trust (WT) 107653/Z/15/Z
6 · The paper itself

Abstract

The unprecedented sequencing efforts during the COVID-19 pandemic paved the way for genomic surveillance to become a powerful tool for monitoring the evolution of circulating viruses. Herein, we discuss how a state-of-the-art artificial intelligence approach called protein language models (pLMs) can be used for effectively analyzing pathogen genomic data. We highlight examples of pLMs applied to predicting viral properties and evolution and lay out a framework for integrating pLMs into genomic surveillance pipelines.

Indexed as

Artificial IntelligenceCOVID-19Genome, ViralGenomicsSARS-CoV-2Evolution, MolecularHumansPandemicsAIgenomic surveillancelanguage modelspLMpublic healthvirus surveillance

Identifiers

PMID39878472
PMCPMC11852828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.