Evidence map›Paper›PMID 39878425›Full record

ArticleClinical and translational gastroenterology2025

Fact or Myth? Black Patients Do Not Want to Participate in Clinical Trials.

Krystal Mills, Francisco Figueroa, RaKetra Knight, Emem Ekpo, Lilian C Lee, Lance Baldo, Chuanbo Xu, Siqi Wang, Robert M Adelman, Priscilla Pemu and 3 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and translational gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04369053 (Prevention of Colorectal Cancer Through Multiomics Blood Testing), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04369053 completednot on this map

Prevention of Colorectal Cancer Through Multiomics Blood Testing

TypeobservationalSponsorFreenome Holdings Inc.Ran2020 to 2024Enrolled48,995ConditionsColon Cancer, Rectal Cancer, Colon Neoplasm, Colon DiseasesArmsFreenome test
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Krystal MillsDepartment of Medicine, Division of Gastroenterology, Morehouse School of Medicine, Atlanta, Georgia, USA.
Francisco FigueroaDepartment of Sociology, University at Buffalo, Buffalo, New York, USA.
RaKetra KnightDepartment of Medicine, Division of Gastroenterology, Morehouse School of Medicine, Atlanta, Georgia, USA.
Emem EkpoDepartment of Medicine, Division of Gastroenterology, Morehouse School of Medicine, Atlanta, Georgia, USA.
Lilian C LeeFreenome Inc, South San Francisco, California, USA.
Lance BaldoFreenome Inc, South San Francisco, California, USA.
Chuanbo XuFreenome Inc, South San Francisco, California, USA.
Siqi WangDepartment of Sociology, University at Buffalo, Buffalo, New York, USA.
Robert M AdelmanDepartment of Sociology, University at Buffalo, Buffalo, New York, USA.
Priscilla PemuDepartment of Medicine, Morehouse School of Medicine, Atlanta, Georgia, USA.
Theodore LevinKaiser Permanente Division of Research, Pleasanton, California, USA.
Aasma ShaukatDepartment of Medicine, Division of Gastroenterology, NYU Grossman School of Medicine, New York, New York, USA .
Julia J LiuDepartment of Medicine, Division of Gastroenterology, Morehouse School of Medicine, Atlanta, Georgia, USA.ORCID 0000-0002-1267-7452

Funding

Freenom Holdings
6 · The paper itself

Abstract

introductionTo assess strategies for optimizing participation of underserved minorities in a blood-based early colorectal cancer detection test study (PREEMPT CRC; NCT04369053) at a hospital serving primarily Black individuals.

methodsCulturally sensitive, racially congruent research staff approached individuals undergoing average-risk screening colonoscopy. Consent/study procedures were synchronized with clinical appointments. Enrolled and not-enrolled patient characteristics were compared. Recruitment was compared with other study sites.

resultsIn total, 247 of 509 eligible individuals were enrolled; most were identified as Black (88.7%). No baseline characteristics were associated with participation. Recruitment was high compared with other sites (11th centile). DISCUSSION: Recruitment barriers for Black individuals can be overcome when easy, culturally sensitive access is facilitated.

Indexed as

Black or African AmericanClinical Trials as TopicColorectal NeoplasmsEarly Detection of CancerPatient SelectionAgedColonoscopyCultural CompetencyFemaleHumansInformed ConsentMaleMiddle Agedclinical trialcolorectal cancerhealth equityinclusionminoritiesrepresentationscreening

Identifiers

PMID39878425
PMCPMC12020698

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.