ArticleEuropean journal of neurology2025
Cross-Country Inequalities in Disease Burden and Quality of Care of Stroke, 1990-2021: A Systematic Analysis of the Global Burden of Disease Study 2021.
Article in European journal of neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Federating European REgistries for Stroke: Principles, Data Model and Future Perspectives for a Federated Analysis of Multiple Prospective Stroke Registries.European journal of neurology · 2026Article
- Implementation of stroke prevention: a review of challenges and opportunities in the Americas.Lancet regional health. Americas · 2026Review
- Global Burden of Pediatric Pulmonary Arterial Hypertension, 1990-2021: A Systematic Analysis from the Global Burden of Disease Study 2021.Pediatric cardiology · 2026Article
- Temporal Trends and Drivers of Socioeconomic Inequalities in Stroke Care, Survival, and Long-Term Outcomes.Journal of the American Heart Association · 2026Article
- Global, regional, and national burden of Early-onset Parkinson's disease: A comprehensive analysis and forecast, 1990-2021.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Global and regional quality of care index in major depressive disorder: the global burden of disease study 2021.International journal for equity in health · 2026Article
- Global quality of care trends for lip and oral cavity cancer: A quality of care index analysis, 1990-2021.Preventive medicine reports · 2026Article
- Global, regional, and national burden of atrial fibrillation and its association with alcohol consumption: age, sex, regional, and SDI differences-an analysis of the Global Burden of Disease Study 2021.Frontiers in cardiovascular medicine · 2026Article
- Global, regional, and national burden of NAFLD in adults aged 20-49 years (1990-2021): a comprehensive analysis of trends, decomposition, and health inequality.BMC gastroenterology · 2025Article
- Global burden, inequalities, frontier dynamics, and risk factors of sudden infant death syndrome, 1990-2021: a systematic analysis from the global burden of disease study 2021.Translational pediatrics · 2025Article
- Burdens of Breast Cancer and Projections for 2030 Among Women in Asia: Findings from the 2021 Global Burden of Disease Study.Current oncology (Toronto, Ont.) · 2025Article
- Global burden and temporal trends of tuberculosis attributable to high sugar-sweetened beverage consumption: insights from the Global Burden of Disease Study 2021.Frontiers in nutrition · 2025Article
- Global, regional, and national burden of neonatal otitis media attributable to PM2.5 air pollution: findings from the Global Burden of Disease study 2021.Frontiers in public health · 2025Article
- Global Burden of Diet High in Processed Meat-related Stroke, 1990-2021.Current neurovascular research · 2025Observational
- Global, regional, and national burden of acute hepatitis (1990-2021): a systematic analysis of the global burden of disease in 2021.Frontiers in medicine · 2025Article
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11 authors.
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Abstract
background and purposeThis study aims to assess the disease burden and care quality along with cross-country inequalities for stroke at global, regional, and national levels from 1990 to 2021.
methodsData on stroke were extracted from the Global Burden of Disease (GBD) study 2021 for the globe, five sociodemographic index (SDI) regions, 21 GBD regions, and 204 countries/territories. The disease burden was quantified using the age-standardized disability-adjusted life years rate (ASDR). Quality of care (QoC) was evaluated through the age-standardized QoC index (QCI). To assess cross-country disparities in both disease burden and age-standardized QCI, the slope index of inequality (SII) and the concentration index were utilized.
resultsFrom 1990 to 2021, the global ASDR of stroke decreased from 3078.95 (95% uncertainty interval [UI]: 2893.58, 3237.34) to 1886.20 (95% UI: 1738.99, 2017.90) per 100,000 population, while the age-standardized QCI improved from 50.79 to 64.61. However, the results of inequalities showed worsening inequalities in both ASDR and QCI, with lower SDI countries shouldering a disproportionate burden and higher SDI countries maintaining higher QoC. The SII and concentration index for ASDR indicated a worsening inequality among lower SDI countries, with SII increasing to -2616.44 and the concentration index increasing to -0.1119 in 2021. Meanwhile, the SII and concentration index for age-standardized QCI showed a worsening inequality among higher SDI countries, with SII of 27.48 and concentration index of 0.0922 in 2021.
conclusionsDespite notable global advancements, significant disparities in stroke still exist, particularly in lower SDI regions facing high disease burdens and substandard care.
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