Evidence map›Paper›PMID 39878351›Full record

ArticleACS chemical neuroscience2025

Synthesis and Evaluation of Benzylic

Niels Knippenberg, Matthias Bauwens, Alexandru Florea, Soma Rudi, Olaf Schijns, Govert Hoogland, Vincent Ornelis, Ronny Mohren, Michiel Vandenbosch, Felix M Mottaghy and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS chemical neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A Ni-Mediated Cross-Coupling Approach to DeuteratedJournal of the American Chemical Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Niels KnippenbergSensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 MD Maastricht, The Netherlands.ORCID 0000-0002-5124-4828
Matthias BauwensInstitute of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, 6200 MD Maastricht, The Netherlands.
Alexandru FloreaDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Centre+ (MUMC+), 6229 HX Maastricht, The Netherlands.
Soma RudiMaastricht Science Programme (MSP), Faculty of Science and Engineering, Maastricht University, 6200 MD Maastricht, The Netherlands.
Olaf SchijnsDepartment of Neurosurgery, Maastricht University Medical Centre+ (MUMC+), 6229 HX Maastricht, The Netherlands.
Govert HooglandDepartment of Neurosurgery, Maastricht University Medical Centre+ (MUMC+), 6229 HX Maastricht, The Netherlands.
Vincent OrnelisSensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 MD Maastricht, The Netherlands.
Ronny MohrenThe Maastricht MultiModal Molecular Imaging (M4I) Institute, Division of Imaging Mass Spectrometry (IMS), Maastricht University, 6229 ER Maastricht, The Netherlands.
Michiel VandenboschThe Maastricht MultiModal Molecular Imaging (M4I) Institute, Division of Imaging Mass Spectrometry (IMS), Maastricht University, 6229 ER Maastricht, The Netherlands.
Felix M MottaghyDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Centre+ (MUMC+), 6229 HX Maastricht, The Netherlands.ORCID 0000-0002-7212-6521
Thomas J CleijSensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 MD Maastricht, The Netherlands.ORCID 0000-0003-0172-9330
Kasper EerselsSensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 MD Maastricht, The Netherlands.ORCID 0000-0002-0214-1320
Bart van GrinsvenSensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 MD Maastricht, The Netherlands.ORCID 0000-0002-6939-0866
Hanne DiliënSensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 MD Maastricht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the main inhibitory neurotransmission system, the GABAergic system poses an interesting yet underutilized target for molecular brain imaging. While PET imaging of postsynaptic GABAergic neurons has been accomplished using radiolabeled benzodiazepines targeting the GABA

Indexed as

BrainFluorine RadioisotopesGABA Plasma Membrane Transport ProteinsNipecotic AcidsPositron-Emission TomographyRadiopharmaceuticalsAnimalsMaleRatsRats, Sprague-DawleyFluorine-18Fluorine RadioisotopesGABA Plasma Membrane Transport Proteinsnipecotic acidNipecotic AcidsRadiopharmaceuticalsfluorine-18GABAGABA transporterpositron emission tomographyradioligand

Identifiers

PMID39878351
PMCPMC11843609

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.