Evidence map›Paper›PMID 39878311›Full record

ArticleeLife2025

MftG is crucial for ethanol metabolism of mycobacteria by linking mycofactocin oxidation to respiration.

Ana Patrícia Graça, Vadim Nikitushkin, Mark Ellerhorst, Cláudia Vilhena, Tilman E Klassert, Andreas Starick, Malte Siemers, Walid K Al-Jammal, Ivan Vilotijevic, Hortense Slevogt and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ana Patrícia GraçaLeibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute, Junior Research Group Synthetic Microbiology, Jena, Germany.
Vadim NikitushkinLeibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute, Junior Research Group Synthetic Microbiology, Jena, Germany.
Mark EllerhorstLeibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute, Junior Research Group Synthetic Microbiology, Jena, Germany.
Cláudia VilhenaLeibniz Institute for Natural Product Research and Infection Biology- Hans Knöll Institute, Department of Infection Biology, Jena, Germany.
Tilman E KlassertRespiratory Infection Dynamics, Helmholtz Centre for Infection Research - HZI Braunschweig, Braunschweig, Germany.
Andreas StarickFriedrich Schiller University Jena, Institute of Microbiology, Jena, Germany.
Malte SiemersFriedrich Schiller University Jena, Institute of Microbiology, Jena, Germany.
Walid K Al-JammalFriedrich Schiller University Jena, Institute of Organic Chemistry and Macromolecular Chemistry, Jena, Germany.
Ivan VilotijevicFriedrich Schiller University Jena, Institute of Organic Chemistry and Macromolecular Chemistry, Jena, Germany.
Hortense SlevogtRespiratory Infection Dynamics, Helmholtz Centre for Infection Research - HZI Braunschweig, Braunschweig, Germany.
Kai PapenfortFriedrich Schiller University Jena, Institute of Microbiology, Jena, Germany.ORCID https://orcid.org/0000-0002-5560-9804
Gerald LacknerLeibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute, Junior Research Group Synthetic Microbiology, Jena, Germany.ORCID https://orcid.org/0000-0002-0307-8319

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycofactocin is a redox cofactor essential for the alcohol metabolism of mycobacteria. While the biosynthesis of mycofactocin is well established, the gene

Indexed as

Bacterial ProteinsEthanolMycobacterium smegmatisOxidoreductasesGene DeletionOxidation-ReductionPeptidesBacterial ProteinsEthanolmycofactocinOxidoreductasesPeptidesbiochemistrychemical biologyinfectious diseasemicrobiologymycobacteriaMycofactocinMycolicibacterium smegmatisoxidoreductaseredox-cofactorrespiration

Identifiers

PMID39878311
PMCPMC11778925

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.