Evidence map›Paper›PMID 39877894›Full record

ArticleIn vitro models2024

Navigating the neuroinflammatory network: insights from diverse cell models.

Libia Catalina Salinas Castellanos, Mayra Micaela Montes, Georgina Oriana Mingolo Malnati, Carina Weissmann

Abstract readEditorial
In one paragraph

Article in In vitro models, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Libia Catalina Salinas CastellanosIFIBYNE-UBA-CONICET, Buenos Aires, Argentina.
Mayra Micaela MontesIFIBYNE-UBA-CONICET, Buenos Aires, Argentina.
Georgina Oriana Mingolo MalnatiIFIBYNE-UBA-CONICET, Buenos Aires, Argentina.
Carina WeissmannIFIBYNE-UBA-CONICET, Buenos Aires, Argentina.ORCID 0000-0002-7196-5390

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this Highlights article, we present insights into the use of simple cell lines in neuroinflammation research, highlighting key findings from our recent investigations. Simple cell lines, including HEK, PC12, SHSY5Y, and N2a cells, provide valuable insights into critical signaling pathways and hidden facets of the neuroinflammatory landscape. Focusing on specific outcomes, including the impact of interleukin-6 (IL-6) and acid-sensing ion channels (ASIC1a), the study sheds light on neuroinflammatory processes. Results showcase the potential of diverse cell models in identifying specific molecules and offer a multidimensional perspective on the intricate neuroinflammatory network, paving the way for therapeutic interventions.

Identifiers

PMID39877894
PMCPMC11756447

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.