Evidence map›Paper›PMID 39877551›Full record

ReviewAJOG global reports2025

Noninferiority of single-incision laparoscopy vs conventional laparoscopy in salpingectomy or salpingotomy for ectopic pregnancy: a meta-analysis.

Greg J Marchand, Ahmed Massoud, Hollie Ulibarri, Amanda Arroyo, Daniela Gonzalez Herrera, Brooke Hamilton, Kate Ruffley, Mckenna Robinson, Marissa Dominick, Ali Azadi

Abstract readReview
In one paragraph

Review in AJOG global reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Greg J MarchandMarchand Institute for Minimally Invasive Surgery, Mesa, AZ (Marchand, Massoud, Ulibarri, Arroyo, Herrera, Hamilton, Ruffley, and Robinson).
Ahmed MassoudMarchand Institute for Minimally Invasive Surgery, Mesa, AZ (Marchand, Massoud, Ulibarri, Arroyo, Herrera, Hamilton, Ruffley, and Robinson).
Hollie UlibarriMarchand Institute for Minimally Invasive Surgery, Mesa, AZ (Marchand, Massoud, Ulibarri, Arroyo, Herrera, Hamilton, Ruffley, and Robinson).
Amanda ArroyoMarchand Institute for Minimally Invasive Surgery, Mesa, AZ (Marchand, Massoud, Ulibarri, Arroyo, Herrera, Hamilton, Ruffley, and Robinson).
Daniela Gonzalez HerreraMarchand Institute for Minimally Invasive Surgery, Mesa, AZ (Marchand, Massoud, Ulibarri, Arroyo, Herrera, Hamilton, Ruffley, and Robinson).
Brooke HamiltonMarchand Institute for Minimally Invasive Surgery, Mesa, AZ (Marchand, Massoud, Ulibarri, Arroyo, Herrera, Hamilton, Ruffley, and Robinson).
Kate RuffleyMarchand Institute for Minimally Invasive Surgery, Mesa, AZ (Marchand, Massoud, Ulibarri, Arroyo, Herrera, Hamilton, Ruffley, and Robinson).
Mckenna RobinsonMarchand Institute for Minimally Invasive Surgery, Mesa, AZ (Marchand, Massoud, Ulibarri, Arroyo, Herrera, Hamilton, Ruffley, and Robinson).
Marissa DominickMidwestern University Chicago College of Osteopathic Medicine, Glendale, AZ (Dominick).
Ali AzadiCollege of Medicine, University of Arizona, Phoenix, AZ (Azadi).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEctopic pregnancy is an emergency frequently requiring laparoscopic intervention. This study aimed to determine whether single-incision laparoscopic surgery is a safe and effective treatment method compared with conventional laparoscopic surgery with multiple ports. DATA SOURCES: This study searched 6 databases from their inception to May 15, 2024, for articles comparing the safety outcomes of single-incision laparoscopic surgery with conventional laparoscopic surgery in managing women with ectopic pregnancy. STUDY ELIGIBILITY CRITERIA: This study included all studies that evaluated the safety outcomes of single-incision laparoscopic surgery compared with conventional laparoscopic surgery in patients with ectopic pregnancy and included at least 1 of our preselected outcomes. In addition, this study included both randomized controlled trials and observational studies.

methodsReview Manager (version 5.4.1) and OpenMetaAnalyst software were used to analyze the extracted data. In addition, this study used odds ratios for dichotomous outcomes, mean difference for continuous outcomes, a fixed effects model for homogeneous outcomes, and a random effects model for heterogeneous outcomes. Furthermore, heterogeneity was evaluated using the

resultsOur analysis showed a significant favoring of the single-incision laparoscopic surgery group in the pain visual analog scale score (median difference=-0.57;

conclusionThe use of single-incision laparoscopic surgery for treating ectopic pregnancy may reduce postoperative pain with similar rates of analgesic use. The incidences of intraoperative and postoperative complications were comparable. Furthermore, the rates of conversion to laparotomy, bowel injury, and postoperative fever were similar between the 2 techniques. Our results seem to show that single-incision laparoscopic surgery is noninferior to conventional laparoscopic surgery for the safe treatment of ectopic pregnancy.

Indexed as

ectopic pregnancylaparoscopysingle incision

Identifiers

PMID39877551
PMCPMC11773238

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.