Evidence map›Paper›PMID 39877338›Full record

ReviewFrontiers in pediatrics2024

Current status and future directions of application of urine proteomics in neonatology.

Dan Wu, Lulu Zhang, Fangrui Ding

Abstract readReview
In one paragraph

Review in Frontiers in pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dan WuTianjin Institute of Obstetrics and Gynecology, Tianjin Central Hospital of Obstetrics and Gynecology, Tianjin, China.
Lulu ZhangTianjin Key Laboratory of Human Development and Reproductive Regulation, Tianjin Central Hospital of Obstetrics and Gynecology, Tianjin, China.
Fangrui DingTianjin Key Laboratory of Human Development and Reproductive Regulation, Tianjin Central Hospital of Obstetrics and Gynecology, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With continuous advancements in mass spectrometry technology, researchers increasingly utilize this method to investigate the molecular mechanisms underlying various diseases, and to identify novel diagnostic and therapeutic strategies. Among proteomics applications, urinary proteomics stands out for its non-invasive nature, making it particularly suitable for vulnerable populations like neonates. This review provides a comprehensive overview of recent research on urinary proteomics in the field of neonatology. It summarizes findings from numerous studies, illustrating how urinary proteomic profiles provide critical insights into neonatal health and disease. By identifying specific protein biomarkers in urine, researchers can gain insights into the early detection and monitoring of neonatal diseases, potentially leading to more timely and effective interventions. As technology evolves, the sensitivity and accuracy of proteomic analyses are expected to improve, opening new avenues for research and clinical applications.

Indexed as

bioinformaticsbiomarker discoverymass spectrometryneonatologyurinary proteomics

Identifiers

PMID39877338
PMCPMC11772477

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.