Evidence map›Paper›PMID 39877318›Full record

ArticleSurgery open science2025

A quantitative amplitude of vagus nerve obtained by intraoperative neuromonitoring predicts postoperative vocal cord paralysis among patients in thyroid/parathyroid surgery as a second option.

Hiroshi Katoh, Riku Okamoto, Kanako Naito, Tomoya Mitsuma, Mariko Kikuchi, Takaaki Tokito, Takeshi Naitoh, Naoki Hiki, Yusuke Kumamoto, Takafumi Sangai

Abstract read
In one paragraph

Article in Surgery open science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hiroshi KatohDepartment of Breast and Thyroid Surgery, Kitasato University Hospital/Kitasato University School of Medicine, Kanagawa, Japan.
Riku OkamotoDepartment of Breast and Thyroid Surgery, Kitasato University Hospital/Kitasato University School of Medicine, Kanagawa, Japan.
Kanako NaitoDepartment of Breast and Thyroid Surgery, Kitasato University Hospital/Kitasato University School of Medicine, Kanagawa, Japan.
Tomoya MitsumaDepartment of Breast and Thyroid Surgery, Kitasato University Hospital/Kitasato University School of Medicine, Kanagawa, Japan.
Mariko KikuchiDepartment of Breast and Thyroid Surgery, Kitasato University Hospital/Kitasato University School of Medicine, Kanagawa, Japan.
Takaaki TokitoDepartment of Breast and Thyroid Surgery, Kitasato University Hospital/Kitasato University School of Medicine, Kanagawa, Japan.
Takeshi NaitohDepartment of Lower Gastrointestinal Surgery, Kitasato University Hospital/Kitasato University School of Medicine, Kanagawa, Japan.
Naoki HikiDepartment of Upper Gastrointestinal Surgery, Kitasato University Hospital/Kitasato University School of Medicine, Kanagawa, Japan.
Yusuke KumamotoDepartment of General-Pediatric-Hepatobiliary Pancreatic Surgery, Kitasato University Hospital/Kitasato University School of Medicine, Kanagawa, Japan.
Takafumi SangaiDepartment of Breast and Thyroid Surgery, Kitasato University Hospital/Kitasato University School of Medicine, Kanagawa, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The advantage of intraoperative neuromonitoring (IONM) has been widely accepted in thyroid/parathyroid surgery. However, there are discrepancies of amplitudes on recurrent laryngeal nerve (RLN) palsy and vocal cord paralysis (VCP) because of amplitude variations among individuals. Accordingly, the universal usefulness of quantitative amplitude value Study design: IONM using a 4-step method (Vagus nerve (V1)-RLN ( Results: Quantitative amplitudes of V2 or R2, and V2/V1 or R2/R1 ratio predicted VCP. The V2 of 117-216 μV predicted VCP with high (>80 %) sensitivity and specificity. Interestingly, the AUC of ROC curve of V2 was the highest, and a cut-off 124 μV of V2 most excellently predicted VCP with the highest sensitivity, specificity, and both positive and negative predictive values. In dissociative analyses, a V2 cut-off 124 μV still excellently predicted VCP in all ranges of initial V1 ≥ 100 μV. In a validation cohort, the V2 of 126-205 μV (cut-off 197 μV) predicted VCP with both high (>80 %) sensitivity and specificity. Conclusions: A quantitative V2 amplitude can predict postoperative VCP among individuals as a simple and a second option, that may be especially useful in some circumstances with unavoidable insufficient initial exposure of vagus nerve.

Indexed as

Intraoperative nerve monitoringParathyroid diseaseQuantitative amplitudeThyroid diseaseVagus nerveVocal cord paralysis

Identifiers

PMID39877318
PMCPMC11773083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.