Evidence map›Paper›PMID 39877108›Full record

ReviewPostepy dermatologii i alergologii2024

Comparative assessment of alcaftadine and olopatadine for allergic conjunctivitis: a meta-analysis.

Xiaojuan Fu, Peijie Xu, Di Lu

Abstract readReview
In one paragraph

Review in Postepy dermatologii i alergologii, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xiaojuan FuChongqing Medical and Pharmaceutical College, Chongqing, China.
Peijie XuChongqing Service Center for Students' Employment, Innovation and Entrepreneurship, Chongqing, China.
Di LuDepartment of Ultrasound, Dianjiang County Hospital of Traditional Chinese Medicine, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: It is unclear to compare the efficacy of alcaftadine versus olopatadine for patients with allergic conjunctivitis, and this meta-analysis aims to perform the comparative assessment of their efficacy for allergic conjunctivitis. Methods: We systematically searched PubMed, Embase, Web of Science, EBSCO, and Cochrane library databases, and included randomized controlled trials (RCTs) comparing alcaftadine with olopatadine for allergic conjunctivitis. The random-effect model was used for the significant heterogeneity, and otherwise the fixed-effect model was used. Results: Twelve RCTs and 1064 patients with allergic conjunctivitis were included in this meta-analysis. In comparison with olopatadine intervention, alcaftadine intervention demonstrated a comparable ocular symptom score on 3 days (MD = -0.06; 95% CI = -0.19 to 0.07; Conclusions: Alcaftadine had better capability to treat allergic conjunctivitis compared to olopatadine.

Indexed as

alcaftadineallergic conjunctivitisolopatadinerandomized controlled trials

Identifiers

PMID39877108
PMCPMC11770579

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.