ArticleResearch square2025
TrimNN: Characterizing cellular community motifs for studying multicellular topological organization in complex tissues.
Yang Yu, Shuang Wang, Jinpu Li, Meichen Yu, Kyle McCrocklin, Jing-Qiong Kang, Anjun Ma, Qin Ma, Dong Xu, Juexin Wang
Abstract readPreprint
In one paragraphArticle in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
10 authors.
Yang YuDepartment of Electrical Engineering and Computer Science, Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA.
Shuang WangDepartment of Computer Science, Luddy School of Informatics, Computing, and Engineering, Indiana University Bloomington, Bloomington, IN 47405, USA.
Meichen YuIndiana Alzheimer's Disease Research Center, Center for Neuroimaging, Department of Radiology and Imaging Sciences, Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA.ORCID https://orcid.org/0000-0003-4551-0269 Kyle McCrocklinDepartment of Biomedical Engineering and Informatics, Luddy School of Informatics, Computing, and Engineering, Indiana University Indianapolis, Indianapolis, IN 46202, USA.
Jing-Qiong KangDepartment of Neurology & Pharmacology, Vanderbilt Kennedy Center of Human Development, University Medical Center, Vanderbilt University, Nashville, TN, 37232, USA.
Juexin WangDepartment of Biomedical Engineering and Informatics, Luddy School of Informatics, Computing, and Engineering, Indiana University Indianapolis, Indianapolis, IN 46202, USA.ORCID https://orcid.org/0000-0002-2260-4310 Funding
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6 · The paper itselfAbstract
The spatial arrangement of cells plays a pivotal role in shaping tissue functions in various biological systems and diseased microenvironments. However, it is still under-investigated of the topological coordinating rules among different cell types as tissue spatial patterns. Here, we introduce the
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PMCPMC11774463
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