Evidence map›Paper›PMID 39876914›Full record

ArticleJournal of medical biochemistry2024

Observation of the clinical characteristics of chronic diarrhoea in children and evaluation of the prognostic value of nutritional and immune indicators.

Jianyun Hao, Xin Ma, Youzhe Gong, Dan Zhu, Huijuan Ning, Xuemei Zhong

Abstract read
In one paragraph

Article in Journal of medical biochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jianyun HaoChildren's Hospital of Capital Institute of Pediatrics, Department of Gastroenterology, Beijing City, China.
Xin MaChildren's Hospital of Capital Institute of Pediatrics, Department of Gastroenterology, Beijing City, China.
Youzhe GongChildren's Hospital of Capital Institute of Pediatrics, Department of Gastroenterology, Beijing City, China.
Dan ZhuChildren's Hospital of Capital Institute of Pediatrics, Department of Gastroenterology, Beijing City, China.
Huijuan NingChildren's Hospital of Capital Institute of Pediatrics, Department of Gastroenterology, Beijing City, China.
Xuemei ZhongChildren's Hospital of Capital Institute of Pediatrics, Department of Gastroenterology, Beijing City, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This research aimed to assess the clinical characteristics of chronic diarrhoea in children and explore the prognostic value of nutritional status and immune indicators. Methods: A total of 190 patients with chronic diarrhoea from January 2017 to June 2020 were enrolled to analyze their epidemiology. The patients were divided into a better prognosis group (cured and improved) and a poor prognosis group (uncured). The efficacy of nutritional status and immune indicators in children's chronic diarrhoea prognosis was analyzed. Results: Most patients were 0-3 years old (74.2%), of which 54.3% were less than 1 year old, and 48.95% had a course of 1 to 2 months. The albumin, immunoglobulin G (IgG), IgA and IgM levels, albumin, globulin, and the ratio of albumin to globulin in the better prognosis group were higher than those in the poor prognosis group. The AUC (area under the curve) of the combined detection in evaluating the prognosis of children with chronic diarrhoea was greater than that of the albumin and globulin alone (P<0.05). IgG 10.05 g/L and IgA 7.72 g/L were protective factors affecting the prognosis of children with chronic diarrhoea. Conclusions: Children with chronic diarrhoea are mainly infants and young children with various clinical symptoms and are prone to comorbidities such as malnutrition, anemia, hypoalbuminemia, and impaired immune function. In evaluating the prognosis of children, evaluating nutritional status and immune indicators together is valuable.

Indexed as

chronic diarrhoeaclinical featuresdiagnostic efficacyimmune indicatorsnutritional statusprognosis

Identifiers

PMID39876914
PMCPMC11771964

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