Evidence map›Paper›PMID 39876890›Full record

ArticleFrontiers in oncology2024

IDH-mutant gliomas in children and adolescents - from biology to clinical trials.

Louise Evans, Sarah Trinder, Andrew Dodgshun, David D Eisenstat, James R Whittle, Jordan R Hansford, Santosh Valvi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Advances in the management of pediatric low-grade glioma.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Louise Evans *Michael Rice Centre for Hematology and Oncology, Women's and Children's Hospital, North Adelaide, SA, Australia.
Sarah Trinder *Kids Cancer Centre, Sydney Children's Hospital, Sydney, NSW, Australia.
Andrew DodgshunDepartment of Pediatrics, University of Otago, Christchurch, New Zealand.
David D EisenstatChildren's Cancer Centre, Royal Children's Hospital, Melbourne, VIC, Australia.
James R WhittleDepartment of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Jordan R Hansford *Michael Rice Centre for Hematology and Oncology, Women's and Children's Hospital, North Adelaide, SA, Australia.
Santosh ValviDepartment of Pediatric and Adolescent Oncology/Hematology, Perth Children's Hospital, Nedlands, WA, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gliomas account for nearly 30% of all primary central nervous system (CNS) tumors in children and adolescents and young adults (AYA), contributing to significant morbidity and mortality. The updated molecular classification of gliomas defines molecularly diverse subtypes with a spectrum of tumors associated with age-distinct incidence. In adults, gliomas are characterized by the presence or absence of mutations in isocitrate dehydrogenase (

Indexed as

adolescent and young adultAYAIDH mutationlow grade gliomapediatric

Identifiers

PMID39876890
PMCPMC11773619

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.