Evidence map›Paper›PMID 39876008›Full record

ArticleDiabetology & metabolic syndrome2025

Glucagon: a potential protective factor against peripheral nerve compromise in patients with type 2 diabetes and obesity.

Hao Hua, Rui Wang, Yu-Xian Xu, Feng Xu, Chun-Hua Wang, Li-Hua Zhao, Li-Hua Wang, Cheng-Wei Duan, Jian-Bin Su

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diabetology & metabolic syndrome, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hao Hua *Department of Endocrinology, Affiliated Hospital 2 of Nantong University, and First People's Hospital of Nantong City, No.666 Shengli Road, Nantong, 226001, China.
Rui Wang *Department of Endocrinology, Affiliated Hospital 2 of Nantong University, and First People's Hospital of Nantong City, No.666 Shengli Road, Nantong, 226001, China.
Yu-Xian XuDepartment of Endocrinology, Affiliated Hospital 2 of Nantong University, and First People's Hospital of Nantong City, No.666 Shengli Road, Nantong, 226001, China.
Feng XuDepartment of Endocrinology, Affiliated Hospital 2 of Nantong University, and First People's Hospital of Nantong City, No.666 Shengli Road, Nantong, 226001, China.
Chun-Hua WangDepartment of Endocrinology, Affiliated Hospital 2 of Nantong University, and First People's Hospital of Nantong City, No.666 Shengli Road, Nantong, 226001, China.
Li-Hua ZhaoDepartment of Endocrinology, Affiliated Hospital 2 of Nantong University, and First People's Hospital of Nantong City, No.666 Shengli Road, Nantong, 226001, China.
Li-Hua WangDepartment of Nursing, Affiliated Hospital 2 of Nantong University, and First People's Hospital of Nantong City, No.666 Shengli Road, Nantong, 226001, China.
Cheng-Wei DuanMedical Research Center, Affiliated Hospital 2 of Nantong University, and First People's Hospital of Nantong City, No.666 Shengli Road, Nantong, 226001, China. chengzi5621@gmail.com.ORCID http://orcid.org/0000-0002-3655-0149
Jian-Bin SuDepartment of Endocrinology, Affiliated Hospital 2 of Nantong University, and First People's Hospital of Nantong City, No.666 Shengli Road, Nantong, 226001, China. sujbzjx@ntu.edu.cn.ORCID http://orcid.org/0000-0002-2138-0263

Funding

Medical Research Project of the Jiangsu Health Commission Z2022058National Natural Science Youth Fund of China 32101027Social Development Projects of Nantong HS2022004Social Development Projects of Nantong MS12019019Social Development Projects of Nantong MS2023083
6 · The paper itself

Abstract

backgroundIncreased glucagon levels are now recognized as a pathophysiological adaptation to counteract overnutrition in type 2 diabetes (T2D). This study aimed to elucidate the role of glucagon in peripheral nerve function in patients with T2D with different body mass indices (BMIs).

methodsWe consecutively enrolled 174 individuals with T2D and obesity (T2D/OB, BMI ≥ 28 kg/m

resultsIn the T2D/OB group, the AUC

conclusionIncreased glucagon levels may be a potential protective factor against peripheral nerve compromise in patients with T2D and obesity.

Indexed as

GlucagonObesityPeripheral nerve functionType 2 diabetes

Identifiers

PMID39876008
PMCPMC11773760

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.