Evidence map›Paper›PMID 39875901›Full record

ArticleBMC complementary medicine and therapies2025

Suhexiang pill for acute ischemic stroke in real-world practice setting (SUNRISE): protocol of a multicenter registry.

Xinxing Lai, Xuejiao Xiong, Qi Jia, Tingting Liu, Zhaowen Yang, Chi Zhang, Lingbo Kong, Kegang Cao, Ting Dong, Caixia Fang and 17 more

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in BMC complementary medicine and therapies, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05833932 (Suhexiang Pill for Acute Ischemic Stroke), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05833932 unknown statusnot on this map

Suhexiang Pill for Acute Ischemic Stroke: A Prospective Registry Study of Real-world Data

Typeobservational_patient_registrySponsorDongzhimen Hospital, BeijingRan2023 to 2024Enrolled1,000ConditionsIschemic StrokeArmsSuhexiang Pill
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Xinxing Lai *Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Xuejiao Xiong *Beijing University of Chinese Medicine, Beijing, China.
Qi Jia *Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Tingting LiuDepartment of Neurology, The Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.
Zhaowen YangDepartment of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Chi ZhangInstitute for Brain Disorders, Beijing University of Chinese Medicine, Beijing, China.
Lingbo KongDepartment of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Kegang CaoDepartment of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Ting DongDepartment of Neurology, The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei, China.
Caixia FangDepartment of Pharmacy, Qingyang People's Hospital, Qingyang, China.
Jianwen GeDepartment of Neurology, Tianshui Hospital of Traditional Chinese Medicine, Tianshui, China.
Li DongDepartment of Neurology, Tianshui Hospital of Traditional Chinese Medicine, Tianshui, China.
Zhitao ZongDepartment of Neurosurgery, Jiujiang First People's Hospital, Jiujiang, China.
Sisi ChenDepartment of Acupuncture and Moxibustion, Jiujiang Hospital of Traditional Chinese Medicine, Jiujiang, China.
Yuhong MaDepartment of Neurology, The Affiliated Hospital of Changzhi Institute of Traditional Chinese Medicine, Changzhi, China.
Xue BaiDepartment of Neurology, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China.
Dahua WuDepartment of Neurology, Hunan Integrated Traditional Chinese and Western Medicine Hospital, Changsha, China.
Yao XieDepartment of Neurology, Hunan Integrated Traditional Chinese and Western Medicine Hospital, Changsha, China.
Mingyan ZhangDepartment of Neurology, Shehong People's Hospital, Shehong, China.
Yilong WangIntensive Care Unit, Shehong People's Hospital, Shehong, China.
Guohui JiangDepartment of Neurology, The Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Daqiao SongDepartment of Neurology, Yiwu Hospital of Traditional Chinese Medicine, Yiwu, China.
Yanping WangDepartment of Neurology, Jiaxing Second Hospital, Jiaxing, China.
Chunyan GuiDepartment of Neurology, Dazhou Central Hospital, Dazhou, China.
Qingwen GengDepartment of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China. gqw4567@163.com.
Ying GaoDepartment of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China. gaoying973@163.com.
SUNRISE study investigators

Funding

China Association for Science and Technology 2021-QNRC1-04China Association of Chinese Medicine 2021XS-001-02, 2021XS-001-05
6 · The paper itself

Abstract

backgroundSuhexiang (SHX) pill is widely used for treating acute ischemic stroke (AIS). Experimental and randomized controlled trials suggested that SHX pill was beneficial for patients with AIS. However, the effectiveness of SHX pill in real-world practice setting remains unclear. It is of great importance to investigate the effectiveness and safety of SHX pill in patients with acute ischemic stroke in real-world clinical practice with long-term follow-up.

methodsThe Suhexiang pill for acute ischemic stroke in Real-world Practice Setting (SUNRISE) is a multicenter, prospective, product-specific, observational study designed to provide insight into the administration of SHX pill for patients with AIS in the real-world clinical practice setting, with an initial sample size of 1000. Eligible patients treated with SHX pill within seven days of AIS onset will be consecutively included in this registry. The primary outcome is the proportion of patients independent at 3 months after stroke onset defined by an mRS score of 0, 1, or 2.

conclusionThe findings of the SUNRISE registry will not only provide insights into the characteristics of patients who may benefit from SHX treatment, but also may enable the individualized treatment decision-making of SHX pill in real-world practice setting. STUDY REGISTRATION: This study was registered with the ClinicalTrials.gov (URL: https://clinicaltrials.gov/ , Unique identifier: NCT05833932).

Indexed as

Drugs, Chinese HerbalIschemic StrokeFemaleHumansMaleMulticenter Studies as TopicProspective StudiesRegistriesDrugs, Chinese HerbalAcute ischemic strokeReal worldRegistrySuhexiang pillTraditional Chinese medicine

Identifiers

PMID39875901
PMCPMC11773706

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