ArticleBMC gastroenterology2025
CT features with histopathological correlation in inflammatory versus benign & malignant neoplastic appendiceal mucoceles: a retrospective cross-sectional study.
Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Tumefactive Crohn's Disease Presenting as Multiple Colonic Mass-Like Lesions Mimicking Colon Carcinoma in a Middle-Aged Man: A Case Report.Clinical case reports · 2026Article
- Laparoscopic management of a huge appendiceal mucocele in a patient with ulcerative colitis: case report and literature review.International journal of surgery case reports · 2026Article
- Incidental Discovery and Removal of an Appendiceal Mucocele in a Patient With Acute Cholecystitis.Cureus · 2026Article
- Comparison of Laparoscopic and Open Surgery for Appendiceal Mucocele in Terms of Safety and Feasibility.JSLS : Journal of the Society of Laparoendoscopic SurgeonsArticle
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9 authors.
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Abstract
BACKGROUND &
objectivesDifferentiation of histologic subtypes of appendiceal mucoceles may prove to be difficult on computed tomography (CT). The main objective of this study was to identify the CT features of mucocele of the appendix and correlate the imaging findings with histopathology in inflammatory, benign, and malignant neoplastic lesions, and whether these entities can be accurately differentiated on CT imaging. MATERIALS AND
methodsCT scans of 31 patients with diagnosis of appendiceal mucocele were retrospectively reviewed and compared with histopathology. The appendix was evaluated for maximal luminal diameter, cystic dilatation, luminal attenuation, appendicolith, mural calcification and enhancement, periappendiceal fat stranding and fluid. CT findings were compared by use of Mann-Whitney U and Fisher's exact tests. Receiver operating characteristics analysis was performed to assess the diagnostic utility of appendiceal luminal diameter in differentiating different types of mucoceles.
resultsPatients were classified into three groups: those with inflammatory mucoceles (n = 10), benign mucoceles (simple mucocele, mucosal hyperplasia and low-grade appendiceal mucinous neoplasm (n = 17), and those with malignant mucinous adenocarcinoma (n = 4). The mean diameter was found to be significantly different in the three groups with the largest diameter in the benign subgroup. Soft tissue thickening (p-value 0.01), mural calcification (p-value < 0.01), internal septation (p-value 0.02) and fat stranding (p-value 0.05) was found to be of statistical significance among the various groups. The best cut-off diameter for diagnosis of inflammatory mucoceles to be ≤ 2.3 cm with a sensitivity of 71% and specificity of 90%.
conclusionOur study suggests that CT findings such as appendiceal diameter less than 2.3 cm, absence of soft tissue thickening, mural calcification and internal septation may be useful in preoperative diagnosis of inflammatory appendiceal mucocele.
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