Evidence map›Paper›PMID 39875835›Full record

ArticleBMC infectious diseases2025

Mortality and immunological indicators of men who have sex with men living with HIV on antiretroviral therapy: a 10-year retrospective cohort study in Southern China.

Huaxiang Lu, Huanhuan Chen, Shujia Liang, Yuhua Ruan, He Jiang, Jinghua Huang, Guangjie Tan, Xiuling Wu, Jianjun Li, Chen Gong and 2 more

Abstract read
In one paragraph

Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Huaxiang Lu *Guangxi Zhuang Autonomous Region Center for Disease Prevention and Control, Nanning, 530028, China. maxpeon@hotmail.com.
Huanhuan Chen *Guangxi Zhuang Autonomous Region Center for Disease Prevention and Control, Nanning, 530028, China.
Shujia Liang *Guangxi Zhuang Autonomous Region Center for Disease Prevention and Control, Nanning, 530028, China.
Yuhua RuanChinese Center for Disease Prevention and Control, Beijing, 102206, China.
He JiangGuangxi Zhuang Autonomous Region Center for Disease Prevention and Control, Nanning, 530028, China.
Jinghua HuangGuangxi Zhuang Autonomous Region Center for Disease Prevention and Control, Nanning, 530028, China.
Guangjie TanGuangxi Zhuang Autonomous Region Center for Disease Prevention and Control, Nanning, 530028, China.
Xiuling WuGuangxi Zhuang Autonomous Region Center for Disease Prevention and Control, Nanning, 530028, China.
Jianjun LiGuangxi Zhuang Autonomous Region Center for Disease Prevention and Control, Nanning, 530028, China.
Chen GongGuangxi Zhuang Autonomous Region Center for Disease Prevention and Control, Nanning, 530028, China.
Qiuying ZhuGuangxi Zhuang Autonomous Region Center for Disease Prevention and Control, Nanning, 530028, China. 271667130@qq.com.
Guanghua LanGuangxi Zhuang Autonomous Region Center for Disease Prevention and Control, Nanning, 530028, China. lgh605@163.com.

Funding

Guangxi Key Laboratory of AIDS Prevention Control and Translation ZZH2020010Guangxi Medical and Health Technology Development and Application Research Project S2024111National Natural Science Foundation of China 82160636National Science and Technology Major Project 2022YFC2305200, 2022YFC2305201
6 · The paper itself

Abstract

backgroundThe proportion of people living with HIV (PLHIV) in Guangxi who are men who have sex with men (MSM) increased rapidly to nearly 10% in 2023; notably, over 95% of this particular population is currently receiving antiretroviral therapy (ART). This study aimed to describe the survival of MSM PLHIV, depict the characteristics and trends of changes in CD4

methodsImmunological indicators of MSM PLHIV receiving ART were extracted and categorized into baseline, mid-treatment, and last values. These were then incorporated into the Cox models in the form of repeated measurements to evaluate the associations (Adjusted-hazard ratios, aHRs) and 95% confidence intervals (95% CIs) of these immunological indicators with mortality at different stages.

resultsA total of 5,642 patients who met the criteria were enrolled in the study, and 160 died, representing a mortality of 2.8%. The first, median, and last values of the CD4

conclusionsMortality among MSM PLHIV on ART in Guangxi is relatively low, and both high viral loads and low CD4

Indexed as

Anti-HIV AgentsCD4-CD8 RatioHIV InfectionsSexual and Gender MinoritiesViral LoadAdultChinaHIVHumansMaleMiddle AgedPrognosisRetrospective StudiesRisk AssessmentSurvival AnalysisYoung AdultAnti-HIV AgentsCD4+/CD8+ T cell ratioCD4+ T cellHIVHomosexualMortalityMSMViral load

Identifiers

PMID39875835
PMCPMC11773718

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.