Evidence map›Paper›PMID 39875778›Full record

ArticleProbiotics and antimicrobial proteins2025

Selenium-Enriched Lactiplantibacillus plantarum ZZU 8-12 Regulates Intestinal Microbiota and Inhibits Acute Liver Injury.

Yanping Wang, Hengyu Ma, Haolong Li, Yuhang Huang, Yupeng Tang, Xiaoxue Tang, Pintian Sun, Zhongfang Tan, Huili Pang, Fengyuan Yang

Abstract read
PubMed Publisher
In one paragraph

Article in Probiotics and antimicrobial proteins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Organic and inorganic selenium-enrichedFrontiers in nutrition · 2026
    Article
  4. Review
  5. Foods (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yanping WangHenan Key Laboratory of Ion Beam Bioengineering, School of Agricultural Sciences, Zhengzhou University, Zhengzhou, 450000, Henan, China.
Hengyu MaHenan Key Laboratory of Ion Beam Bioengineering, School of Agricultural Sciences, Zhengzhou University, Zhengzhou, 450000, Henan, China.
Haolong LiHenan Key Laboratory of Ion Beam Bioengineering, School of Agricultural Sciences, Zhengzhou University, Zhengzhou, 450000, Henan, China.
Yuhang HuangHenan Key Laboratory of Ion Beam Bioengineering, School of Agricultural Sciences, Zhengzhou University, Zhengzhou, 450000, Henan, China.
Yupeng TangHenan Key Laboratory of Ion Beam Bioengineering, School of Agricultural Sciences, Zhengzhou University, Zhengzhou, 450000, Henan, China.
Xiaoxue TangHenan Key Laboratory of Ion Beam Bioengineering, School of Agricultural Sciences, Zhengzhou University, Zhengzhou, 450000, Henan, China.
Pintian SunHenan Key Laboratory of Ion Beam Bioengineering, School of Agricultural Sciences, Zhengzhou University, Zhengzhou, 450000, Henan, China.
Zhongfang TanHenan Key Laboratory of Ion Beam Bioengineering, School of Agricultural Sciences, Zhengzhou University, Zhengzhou, 450000, Henan, China.
Huili PangHenan Key Laboratory of Ion Beam Bioengineering, School of Agricultural Sciences, Zhengzhou University, Zhengzhou, 450000, Henan, China.
Fengyuan YangTianjian Laboratory of Advanced Biomedical Sciences, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, 450000, Henan, China. yangfy_zzu@outlook.com.

Funding

Key Project of the Second Batch of the Joint Fund of the 2022 Provincial Plan for Scientific and Technological Research and Development 225200810037National Natural Science Foundation of China 31772672
6 · The paper itself

Abstract

Intake of certain Lactiplantibacillus strains was recognized as a potential strategy for acute liver injury (ALI) prevention. This study is aimed at developing a selenium-enriched Lactiplantibacillus strain-based ALI prevention strategy. L. plantarum ZZU 8-12 was isolated from human fecal sample and screened out based on its adaption to intestinal microenvironment, inhibitive capability against pathogenic bacteria, and in vivo anti-inflammation response in DSS-induced colitis mice model. The strain was applied as a producer of nano selenium particles to produce selenium-enriched L. plantarum ZZU 8-12. Intake of selenium-enriched L. plantarum ZZU 8-12 upregulated the abundance of short-chain fatty acid-producing genera including Lactiplantibacillus, Phascolarctobacterium, Butyricicoccus, and Clostridiales bacterium in fecal microbiota and thus inhibited ALI induced by CCL

Indexed as

Chemical and Drug Induced Liver InjuryGastrointestinal MicrobiomeLactiplantibacillus plantarumProbioticsSeleniumAnimalsColitisFecesHumansMaleMiceMice, Inbred C57BLSeleniumAcute liver injuryIntestinal microbiotaL. plantarumNano selenium particle

Identifiers

PMID39875778

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.