Evidence map›Paper›PMID 39875730›Full record

SynthesisEuropean archives of psychiatry and clinical neuroscience2025

Common and distinct neural patterns of gray matter alterations in adults with anorexia nervosa and obsessive-compulsive disorder.

Xinyue Wan, Pengfei Zhang, Yanli Jiang, Guangyao Liu, Laiyang Ma, Jing Zhang, Jun Zhang

Erratum issuedAbstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in European archives of psychiatry and clinical neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Xinyue Wan *Department of Radiology, Huashan Hospital, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.
Pengfei Zhang *Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, Chengdu, China.
Yanli JiangSecond Clinical School, Lanzhou University, Lanzhou, China.
Guangyao LiuDepartment of Magnetic Resonance, Lanzhou University Second Hospital, Lanzhou, China.
Laiyang MaSecond Clinical School, Lanzhou University, Lanzhou, China.
Jing ZhangSecond Clinical School, Lanzhou University, Lanzhou, China. ery_zhangjing@lzu.edu.cn.
Jun ZhangDepartment of Radiology, Huashan Hospital, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China. zhangjun_zj@fudan.edu.cn.

Funding

Gansu Province Clinical Research Center for Functional and Molecular Imaging 21JR7RA438National Key R&D Program of China 2022YFF0708700National Natural Science Foundation of China 81960309Shanghai Academic Research Leader Program 21XD1420900Shanghai Municipal Commission of Health Program 20224Z0002Student Scientific Research Program (Fuqing Scholar) of Shanghai Medical College, Fudan University FQXZ202206B
6 · The paper itself

Abstract

Anorexia nervosa (AN) and obsessive-compulsive disorder (OCD) often share multiple similar symptoms and are highly comorbid; however, the common and distinct brain neuroanatomy of these two diseases are unclear. The current study attempted to identify the overlapping and different gray matter volume (GMV) between AN and OCD. We conducted a voxel-wise meta-analysis of GMV using the latest Seed-based d Mapping with Permutation of Subject Images Toolbox (SDM-PSI) software. Compared to healthy controls, patients with AN showed reduced GMV in supplementary motor areas, median cingulate cortices, the left cerebellum, right Rolandic operculum (RO), right insula, right superior temporal gyrus (STG), and right precuneus, while OCD patients were characterized by low GMV in the right insula, STG, RO, and inferior frontal gyrus (IFG). The conjunctional analysis indicated that these two disorders have overlapping structural abnormalities in the right insula, STG, RO and IFG. No distinct GMV alteration was found. These common structural brain abnormalities may underlie the neuropathology of the similar neuropsychological features and highly comorbid manifestations of AN and OCD.

Indexed as

Anorexia NervosaBrainGray MatterObsessive-Compulsive DisorderAdultFemaleHumansMagnetic Resonance ImagingMaleYoung AdultAnorexia nervosaMeta-analysisObsessive-compulsive disorderVoxel-based morphometry

Identifiers

PMID39875730

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.