Evidence map›Paper›PMID 39875714›Full record

ArticleClinical oral investigations2025

Different essential oils can inhibit Candida albicans biofilm formation on acrylic resin by suppressing aspartic proteinase: In vitro and in silico approaches.

Nurdan Polat Sağsöz, Leyla Güven, Bahri Gür, Canan Vejselova Sezer, Mustafa Cengiz, Figen Orhan, Özlem Barış

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nurdan Polat Sağsöz *Department of Prosthodontics, Faculty of Dentistry, Atatürk University, Erzurum, Türkiye. nurdan.sagsoz@atauni.edu.tr.
Leyla Güven *Department of Pharmaceutical Botany, Faculty of Pharmacy, Ataturk University, Erzurum, Türkiye. leyla.guven@atauni.edu.tr.
Bahri GürDepartment of Biochemistry, Faculty of Sciences and Arts, Iğdır University, Iğdır, Türkiye.
Canan Vejselova SezerDepartment of Biology, Faculty of Science, Eskişehir Technical University, Eskişehir, Türkiye.
Mustafa CengizDepartment of Elementary Education, Faculty of Education, Siirt University, Siirt, Türkiye.
Figen OrhanVocational School of Health Services, Ataturk University, Erzurum, Türkiye.
Özlem BarışDepartment of Biology, Science Faculty, Atatürk University, Erzurum, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCymbopogon martini, Syzygium aromaticum, and Cupressus sempervirens are used for antimicrobial purposes in the worldwide. Both their extracts and essential oil contents are rich in active ingredients.

objectiveThe aim of this study was to investigate the inhibitory effect of Cymbopogon martini essential oil (CMEO), Syzygium aromaticum essential oil (SAEO) and Cupressus sempervirens essential oil (CSEO) on Candida albicans biofilm formation on heat-polymerized polymethyl methacrylate (PMMA) samples in vitro and in silico. MATERIALS AND

methodsEssential oil contents with anticandidal potential were determined by Gas Chromatography-Mass Spectrometry. Following C. albicans adhesion, PMMA samples were treated independently with Corega

results2% of CMEO and 5% of SAEO exhibited higher anticandidal activity than Corega

conclusionsThe biofilm formation of C. albicans onto acrylic resin was inhibited by CMEO, SAEO and CSEO at a concentration of 2% through in vitro assay. The most effective inhibition was determined to be due to citronellol in CMEO through in silico analysis.

Indexed as

Acrylic ResinsAntifungal AgentsAspartic Acid ProteasesBiofilmsCandida albicansOils, VolatileAnimalsComputer SimulationCymbopogonGas Chromatography-Mass SpectrometryIn Vitro TechniquesMiceMicrobial Sensitivity TestsPolymethyl MethacrylateSyzygiumAcrylic ResinsAntifungal AgentsAspartic Acid ProteasesOils, VolatilePolymethyl MethacrylateAcrylic resinAnticandidal activityDenture cleanserMolecular modelingSecreted aspartic proteinase

Identifiers

PMID39875714

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.