Evidence map›Paper›PMID 39875674›Full record

ReviewNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2025

Multiple system atrophy related neurogenic bladder: mechanism and treatment.

Gengqing Ren, Yao Wang, Hao Tian, Kaige Zhang, Han Zhang, Xiaoxu Liu, Zhigang Chen

Abstract readReview
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In one paragraph

Review in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gengqing RenBeijing University of Chinese Medicine, Beijing, 100029, China.
Yao WangTsinghua University, Beijing, 100084, China.
Hao TianBeijing University of Chinese Medicine, Beijing, 100029, China.
Kaige ZhangBeijing University of Chinese Medicine, Beijing, 100029, China.
Han ZhangBeijing University of Chinese Medicine, Beijing, 100029, China.
Xiaoxu LiuBeijing University of Chinese Medicine, Beijing, 100029, China.
Zhigang ChenNeurology Department One, Dongfang Hospital, Beijing University of Chinese Medicine, No. 6, Fangxingyuan Community, Fangzhuang, Fengtai District, Beijing, 100078, People's Republic of China. chenzhigang64@126.com.ORCID http://orcid.org/0000-0002-9675-5920

Funding

National Natural Science Foundation of China 82174328
6 · The paper itself

Abstract

backgroundMultiple system atrophy (MSA) is a progressive neurodegenerative disease characterized by its aggressive nature. Its main clinical features include autonomic dysfunction, Parkinson's disease, and cerebellar ataxia.

methodsWe conducted a comprehensive review of the existing literature, exploring studies and reports related to the mechanisms and treatment of multiple system atrophy related neurogenic bladder. Our aim is to provide a detailed and up-to-date overview of its underlying pathophysiology and current therapeutic strategies. RESULTS AND

conclusionNeurogenic bladder, a common manifestation of MSA, often goes untreated or mistreated, significantly affecting patients' quality of life. Early-stage bladder dysfunction is frequent in MSA patients and correlates with disease severity. The mechanisms of MSA related neurogenic bladder are related to the autonomic nervous system, somatic nerves, frontal cortex, brainstem, and sacral medulla center. Currently, treatment for MSA related neurogenic bladder is mainly symptomatic, and specific drugs are lacking. Further in-depth research is needed to develop more effective therapeutic options that improve patients' quality of life and reduce the risk of complications.

Indexed as

Multiple System AtrophyUrinary Bladder, NeurogenicHumansMultiple system atrophyNeurodegenerative diseaseNeurogenic bladderUrinary incontinenceUrine retention

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.