Evidence map›Paper›PMID 39875624›Full record

SynthesisJournal of gastrointestinal cancer2025

Comparing Operative Outcomes and Resection Quality in Robotic vs Open Pancreaticoduodenectomy: A Meta-analysis of 54,000 Patients.

Muhammad Hassan Waseem, Zain Ul Abideen, Rafia Durrani, Esha Dilawar, Mohammad Saboor Kamran, Hassan Tariq Butt, Haseeb Javed Khan, Abdul Ahad, Pakeeza Shakoor, Hema Kumari Jeswani and 5 more

Abstract readComparative StudyMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of gastrointestinal cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Muhammad Hassan WaseemAllama Iqbal Medical College, Lahore, Pakistan.
Zain Ul AbideenKing Edward Medical University, H897+X5V Chowk, Nila Gumbad Rd, Neela Gumbad, Lahore, 54000, Punjab, Pakistan. mzainulabideen@kemu.edu.pk.
Rafia DurraniAga Khan University, Karachi, Pakistan.
Esha DilawarServices Institute of Medical Sciences, Lahore, Pakistan.
Mohammad Saboor KamranZiauddin University, Karachi, Pakistan.
Hassan Tariq ButtFederal Medical College, Islamabad, Pakistan.
Haseeb Javed KhanKing Edward Medical University, H897+X5V Chowk, Nila Gumbad Rd, Neela Gumbad, Lahore, 54000, Punjab, Pakistan.
Abdul AhadKhyber Medical College, Peshawar, Pakistan.
Pakeeza ShakoorAbbasi Shaheed Hospital, Karachi, Pakistan.
Hema Kumari JeswaniJinnah Sindh Medical University, Karachi, Pakistan.
Syeda Aliza KazmiKing Edward Medical University, H897+X5V Chowk, Nila Gumbad Rd, Neela Gumbad, Lahore, 54000, Punjab, Pakistan.
Ibrahim MugheesGhurki Trust and Teaching Hospital, Lahore, Pakistan.
Muhammad AliAllama Iqbal Teaching Hospital, Dera Ghazi Khan, Pakistan.
Muhammad Arslan TariqAllama Iqbal Medical College, Lahore, Pakistan.
Shurjeel Uddin QaziDow University of Health Sciences, Karachi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh morbidity and mortality make pancreaticoduodenectomy (PD) one of the most complicated surgical procedures. This meta-analysis aimed to compare the outcomes of robotic pancreaticoduodenectomy (RPD) versus open pancreaticoduodenectomy (OPD).

methodA comprehensive literature search of PubMed, Cochrane Central, and Google Scholar was conducted from inception to November 2024. Studies comparing RPD and OPD in adults aged ≥ 18 years were included. Data for the outcomes of interest were extracted.

resultsForty-one studies with a total of 54,287 patients were pooled. RPD is significantly superior to OPD in terms of overall postoperative complications (RR = 0.91, 95% CI: [0.86-0.97]; p = 0.001), wound infections (RR = 0.63, 95% CI: [0.49-0.81], p = 0.0004), estimated blood loss (WMD = -171.99 ml, 95% CI: [ -217.76 to -126.22], p < 0.01) and hospitalization duration (WMD = -1.33 days, 95% CI: [ -1.84 to -0.82], p < 0.01) with a longer operating time (WMD = 73.22 min, 95% CI: [56.20 to 90.23], p < 0.01).

conclusionIn conclusion, RPD shows a lower risk of wound infections and overall postoperative morbidity compared to OPD. It has lower estimated blood loss, shorter hospitalization duration, and a longer operating time. The two approaches were comparable in terms of resection quality. More high-quality RCTs are required to draw definite conclusions.

Indexed as

Pancreatic NeoplasmsPancreaticoduodenectomyPostoperative ComplicationsRobotic Surgical ProceduresBlood Loss, SurgicalHumansLength of StayOperative TimeTreatment OutcomeMeta-analysisPancreaticoduodenectomyRobotic pancreaticoduodenectomySystematic reviewWhipple

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.