Evidence map›Paper›PMID 39875098›Full record

ArticleOpen biology2025

Targeting of retrovirus-derived

Yoshifumi Fujioka, Hirosuke Shiura, Masayuki Ishii, Ryuichi Ono, Tsutomu Endo, Hiroshi Kiyonari, Yoshikazu Hirate, Hikaru Ito, Masami Kanai-Azuma, Takashi Kohda and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yoshifumi FujiokaDepartment of Epigenetics, Medical Research Institute (MRI), Tokyo Medical and Dental University (TMDU), Tokyo 113-8510, Japan.
Hirosuke ShiuraDepartment of Epigenetics, Medical Research Institute (MRI), Tokyo Medical and Dental University (TMDU), Tokyo 113-8510, Japan.
Masayuki IshiiDepartment of Epigenetics, Medical Research Institute (MRI), Tokyo Medical and Dental University (TMDU), Tokyo 113-8510, Japan.
Ryuichi OnoDepartment of Epigenetics, Medical Research Institute (MRI), Tokyo Medical and Dental University (TMDU), Tokyo 113-8510, Japan.
Tsutomu EndoCenter for Experimental Animals, TMDU, Tokyo 113-8510, Japan.
Hiroshi KiyonariLaboratory for Animal Resources and Genetic Engineering, RIKEN Center for Biosystems Dynamics Research, Kobe, Hyogo 650-0047, Japan.
Yoshikazu HirateCenter for Experimental Animals, TMDU, Tokyo 113-8510, Japan.
Hikaru ItoCenter for Experimental Animals, TMDU, Tokyo 113-8510, Japan.
Masami Kanai-AzumaCenter for Experimental Animals, TMDU, Tokyo 113-8510, Japan.
Takashi KohdaFaculty of Life and Environmental Sciences, University of Yamanashi, Kohfu, Yamanashi 400-8510, Japan.
Tomoko Kaneko-IshinoFaculty of Nursing, Tokai University School of Medicine, Isehara, Kanagawa 259-1193, Japan.
Fumitoshi IshinoDepartment of Epigenetics, Medical Research Institute (MRI), Tokyo Medical and Dental University (TMDU), Tokyo 113-8510, Japan.ORCID 0000-0001-8458-6069

Funding

Japan Society for the Promotion of ScienceTokyo Medical and Dental University
6 · The paper itself

Abstract

Retrotransposon Gag-like (RTL) 8A, 8B and 8C are eutherian-specific genes derived from a certain retrovirus. They cluster as a triplet of genes on the X chromosome, but their function remains unknown. Here, we demonstrate that

Indexed as

ObesityRetroelementsRetroviridaeSocial BehaviorAnimalsBehavior, AnimalDisease Models, AnimalMaleMiceMice, KnockoutRetroelementsapathylate-onset obesityneuronal developmentPrader–Willi syndromeretrovirus-derived genessocial response

Identifiers

PMID39875098
PMCPMC11774587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.