Evidence map›Paper›PMID 39874177›Full record

ArticleEuropean heart journal2025

Incident heart failure and recurrent coronary events following acute myocardial infarction.

Javed Butler, Kendall Hammonds, Khawaja M Talha, Ayman Alhamdow, Monica M Bennett, J Vee Anne Bomar, Jason A Ettlinger, Monica Martinez Traba, Elisa L Priest, Niklas Schmedt and 7 more

Abstract readMulticenter Study
In one paragraph

Article in European heart journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Javed ButlerBaylor Scott & White Research Institute, 3434 Live Oak St Ste 501, Dallas, TX 75204, USA.ORCID 0000-0001-7683-4720
Kendall HammondsBaylor Scott & White Research Institute, 3434 Live Oak St Ste 501, Dallas, TX 75204, USA.
Khawaja M TalhaDepartment of Medicine, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA.
Ayman AlhamdowBoehringer Ingelheim International GmbH, Binger Straße 173, Ingelheim, 55218 Ingelheim am Rhein, Germany.
Monica M BennettBaylor Scott & White Research Institute, 3434 Live Oak St Ste 501, Dallas, TX 75204, USA.
J Vee Anne BomarBaylor Scott & White Research Institute, 3434 Live Oak St Ste 501, Dallas, TX 75204, USA.
Jason A EttlingerBaylor Scott & White Research Institute, 3434 Live Oak St Ste 501, Dallas, TX 75204, USA.
Monica Martinez TrabaBoehringer Ingelheim International GmbH, Binger Straße 173, Ingelheim, 55218 Ingelheim am Rhein, Germany.
Elisa L PriestBaylor Scott & White Research Institute, 3434 Live Oak St Ste 501, Dallas, TX 75204, USA.ORCID 0000-0003-0474-6275
Niklas SchmedtBoehringer Ingelheim International GmbH, Binger Straße 173, Ingelheim, 55218 Ingelheim am Rhein, Germany.
Cecilia ZeballosBoehringer Ingelheim International GmbH, Binger Straße 173, Ingelheim, 55218 Ingelheim am Rhein, Germany.
Courtney N ShaverBaylor Scott & White Research Institute, 3434 Live Oak St Ste 501, Dallas, TX 75204, USA.ORCID 0000-0002-9936-4597
Aasim AfzalDepartments of Cardiology and Cardiothoracic Surgery, Baylor Scott &White The Heart Hospital, 1100 Allied Dr, Plano, TX 75093, USA.ORCID 0000-0003-1557-8190
Robert J WidmerDepartment of Cardiology, Baylor Scott & White Medical Center-Temple, 2401 S 31st St, Temple, TX 76508, USA.
Robert L GottliebBaylor Scott & White Research Institute, 3434 Live Oak St Ste 501, Dallas, TX 75204, USA.ORCID 0000-0001-8376-8709
Michael J MackBaylor Scott & White Research Institute, 3434 Live Oak St Ste 501, Dallas, TX 75204, USA.
Milton PackerCenter for Advanced Heart and Lung Disease and Baylor Heart and Vascular Institute, Baylor University Medical Center, 3410 Worth St, Ste 250, Dallas, TX 75226, USA.

Funding

Boehringer IngelheimCompany Diabetes AllianceEli LillyEli Lilly and Company
6 · The paper itself

Abstract

BACKGROUND AND

aimsRecurrent myocardial infarction (MI) and incident heart failure (HF) are major post-MI complications. Herein, contemporary post-MI risks for recurrent MI and HF are described.

methodsA total of 6804 patients with a primary discharge diagnosis of MI at 28 Baylor Scott & White Health hospitals (January 2015 to December 2021) were studied. Patient characteristics, treatment, and outcomes, including incident HF, recurrent MI, all-cause death, and all-cause and cardiovascular rehospitalizations, were assessed. Landmark approach anchored at 3 months post-discharge was used to assess 1-year outcomes.

resultsMedian age was 69 years, 59.7% were male, and 76.7% had non-ST-elevation MI. Comorbidities included hypertension (89%), dyslipidaemia (87%), Type 2 diabetes (48%), and chronic kidney disease (34%); 17% had a history of MI and 23% of HF; 63% underwent percutaneous/surgical revascularization. In landmark-anchored 1-year outcomes (N = 6210), 413 (6.7%) patients died, 1730 (27.9%) had all-cause and 735 (11.8%) cardiovascular hospitalizations, 234 (3.8%) had recurrent MI. Of patients without history of HF, 1160 (23.8%) developed incident HF [42.2%, 26.7%, and 31.1% with ejection fraction (EF) < 40%, 41-49%, and >50%, respectively) within 3 months of discharge. Patients who developed HF had higher risk of death and hospitalizations (all P < .001), irrespective of EF. Of 2179 patients with EF > 50% without prevalent HF or HF during index hospitalization, 257 (11.8%) developed HF and 77 (3.5%) recurrent MI within 1 year.

conclusionsIn a contemporary post-MI cohort, the risk for incident HF was greater than recurrent MI, even among those with normal EF and no HF at discharge.

Indexed as

Heart FailureMyocardial InfarctionAgedFemaleHospitalizationHumansIncidenceMaleMiddle AgedPatient ReadmissionRecurrenceRisk FactorsEpidemiologyHeart failureMortalityMyocardial infarctionRegistry

Identifiers

PMID39874177
PMCPMC12011519

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.