Evidence map›Paper›PMID 39873836›Full record

ArticleMolecular biology reports2025

Molecular docking and differential rbcl gene expression reveal variation in glyphosate herbicide tolerance of sugarcane varieties.

Kawthr S M Allam, M Magdy, A M Abd El-Aal, Nasr S Khalil, M A Rashed, A H Atta, Reham I AbdelHamid

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Article in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Kawthr S M AllamGenetics Department, Faculty of Agriculture, Ain Shams University, Cairo, Egypt.
M MagdyGenetics Department, Faculty of Agriculture, Ain Shams University, Cairo, Egypt.
A M Abd El-AalAgricultural Research Center(ARC), Sugar Crops Research Institute(SCRI), Giza, Egypt.
Nasr S KhalilDepartment of Pesticides Analysis Research, Center Agricultural Pesticides Laboratory, Agricultural Research Center, Giza, Egypt.
M A RashedGenetics Department, Faculty of Agriculture, Ain Shams University, Cairo, Egypt.
A H AttaGenetics Department, Faculty of Agriculture, Ain Shams University, Cairo, Egypt.
Reham I AbdelHamidAgricultural Research Center(ARC), Sugar Crops Research Institute(SCRI), Giza, Egypt. RehamIbrahim@agr.asu.edu.eg.ORCID http://orcid.org/0000-0002-2738-4839

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGlyphosate is an extensively employed herbicide in agriculture, specifically for sugarcane cultivation. The situation is different with the extensive physiological and genetic effects exerted by this herbicide on a range of plant species, including sugarcane, whose model basis is still poorly characterized, although its primary mode of action, which acts on the EPSPS enzyme in the shikimic acid pathway, is completely elucidated. The current study was aimed at investigating the stability of glyphosate formulation, molecular interactions of glyphosate formulation with rbcL enzyme associated with chlorophyll metabolism, and its effects on varieties of sugarcane. METHODS AND

resultsThe stability of a ground-up glyphosate formulation was assessed under accelerated storage conditions. Molecular docking was performed to analyze interactions between glyphosate derivatives and rbcL. Two sugarcane varieties (G84-47 and GT54-9) were treated with increasing glyphosate concentrations (0.2, 0.4, and 0.8 mg L

conclusionsThis study reveals genetic variability in sugarcane responses to glyphosate, with variety-specific mechanisms underlying stress adaptation. The inducible rbcL expression in tolerant varieties provides insights into herbicide resistance mechanisms. These findings can inform marker-assisted breeding and improve agronomic practices for enhanced sugarcane cultivation resilience and sustainability.

Indexed as

GlycineHerbicide ResistanceHerbicidesRibulose-Bisphosphate CarboxylaseSaccharumChlorophyllGene Expression Regulation, PlantGlyphosateMolecular Docking SimulationPlant ProteinsChlorophyllGlycineGlyphosateHerbicidesPlant ProteinsRibulose-Bisphosphate CarboxylaseGene expressionGlyphosateHerbicide toleranceMolecular dockingrbcLSugarcane

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PMID39873836

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.