Evidence map›Paper›PMID 39873774›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Long-term efficacy of superior laryngeal nerve block for the treatment of chronic neurogenic cough.

Tanner J Diemer, Brian A Keith, Shaun A Nguyen, Ashli K O'Rourke

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Effect of Superior Laryngeal Nerve Block for Neurogenic Cough: A Single-Arm Meta-Analysis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Pooled it
  2. Pooled it
  3. Efficacy and safety of superior laryngeal nerve block in neurogenic cough: A systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Pooled it
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tanner J DiemerMedical University of South Carolina, 135 Rutledge Ave, Charleston, SC, 29425, USA. tjd1@arizona.edu.ORCID http://orcid.org/0009-0003-7508-4659
Brian A KeithMedical University of South Carolina, 135 Rutledge Ave, Charleston, SC, 29425, USA.ORCID http://orcid.org/0009-0002-8499-2440
Shaun A NguyenMedical University of South Carolina, 135 Rutledge Ave, Charleston, SC, 29425, USA.ORCID http://orcid.org/0000-0003-0664-4571
Ashli K O'RourkeMedical University of South Carolina, 135 Rutledge Ave, Charleston, SC, 29425, USA.ORCID http://orcid.org/0000-0002-1293-501X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe study aimed to evaluate the long-term efficacy and safety of superior laryngeal nerve (SLN) block for treating chronic neurogenic cough (CNC) in a large patient cohort.

methodsA retrospective review was conducted on patients treated between January 2019 and October 2023. Data collected included patient demographics, number of injections, follow-up times, subjective cough severity, and Leicester Cough Questionnaire (LCQ) scores.

resultsAmong 117 patients (76.1% female; mean age 66.1), the median number of injections was 3, with a median follow-up duration of 4 weeks. Subjective improvement was reported in 74.4% of cases, with mild adverse events occurring in 8.4% of injections. Regression analysis showed a strong correlation between decreased subjective severity and time. LCQ scores improved slightly within 1-3 months and 25-40 months.

conclusionThe findings suggest that SLN blocks effectively reduce subjective severity and improve LCQ scores long-term, with sequential injections potentially reducing chronic steroid use risks. Further prospective studies are recommended to optimize dosing intervals.

Indexed as

CoughLaryngeal NervesNerve BlockAdultAgedAnesthetics, LocalChronic DiseaseFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeAnesthetics, LocalChronic coughCoughLaryngologyNeurogenic coughSuperior laryngeal nerve block

Identifiers

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.