Observational studyOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2025
Time trend analysis of osteoporosis prevalence among adults 50 years of age and older in the USA, 2005-2018.
Observational study in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Fragility fracture risk prediction using quantitative magnetic resonance and Vertebral Bone Quality scoring beyond density.World journal of methodology · 2026Review
- Multi-center validation of automated CT-based L1 vertebral Hounsfield unit.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Sex and age-specific medication interaction in osteoporosis risk.GeroScience · 2026Article
- Trends and disparities in DXA testing for osteoporosis among Medicare beneficiaries, 2005-2023.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- The osteoporosis care cascade in postmenopausal women with and without cardiovascular disease: a nationally representative cross-sectional study using dual-energy X-ray absorptiometry.Archives of osteoporosis · 2026Article
- Calcium isotope ratio (δOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Osteoporosis is a risk factor for complications and reoperations at 1 and 3 years after arthroscopic rotator cuff repair.JSES international · 2026Article
- Shoulder arthroplasty in the osteoporotic patient: do bisphosphonates make a difference?JSES international · 2026Article
- Cortical Bone Loss in Barcelona Across Time (1st Century CE-18th Century CE) and Its Potential Relationship With Linear Enamel Hypoplasia.American journal of biological anthropology · 2026Article
- A Comparative Evaluation of Three Time-to-Event Models Predicting 5-Year Osteoporosis Risk in Thyroid Cancer Survivors: A Nationwide Cohort Study.Endocrinology and metabolism (Seoul, Korea) · 2026Article
- Alternative Osteoporosis Therapies After Bisphosphonate Associated Atypical Femur Fractures: A Retrospective Analysis.Geriatric orthopaedic surgery & rehabilitation · 2026Article
- OsteoStrong and bone health: a scoping review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Article
- No obvious time trend in proximal humeral fracture complexity : a cohort study from 1944 to 2020 in Malmö, Sweden.Bone & joint open · 2025Article
- The Role of Senolytics in Osteoporosis.Biomolecules · 2025Review
- What is the patient-reported outcome, complication rate and conversion to total knee arthroplasty in patients with tibial plateau fractures caused by high-energy compared to low-energy mechanisms of injury?European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Article
- Pulsed electromagnetic field prevents lumbar bone loss in orchiectomy mice without altering systemic iron metabolism.Frontiers in bioengineering and biotechnology · 2025Article
- Global epidemiology, burden, and causes of lower extremity and pelvic fractures in the past 32 years.Frontiers in public health · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
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Abstract
Using data from NHANES for years 2005-2018, we examined temporal trends in osteoporosis prevalence and the proportion of undiagnosed osteoporosis in the United States of America. Our results suggested statistically significant increases in osteoporosis prevalence across several demographic groups. These findings carry profound implications for public health, given increased life expectancy and burden of chronic diseases.
introductionThis is the first study to assess osteoporosis prevalence trends over time and the proportion of undiagnosed osteoporosis across gender, ethnicity/race, and age groups.
methodsObservational time trend analyses were conducted using the 2005-2006, 2007-2008, 2009-2010, 2013-2014, and 2017-2018 National Health and Nutrition Examination Survey (NHANES) datasets, along with a descriptive analysis using the 2017-2018 NHANES dataset to capture the proportion of undiagnosed osteoporosis.
resultsThe findings showed a statistically significant increase in osteoporosis prevalence among women, non-Hispanic Whites, and all age groups (except for individuals 80 years of age and older) during the study period. A subsequent analysis examining individuals by both gender and ethnicity/race demonstrated a statistically significant increase among Other Hispanic men and non-Hispanic White women. Additional descriptive analyses found that 69.12% of individuals with osteoporosis went undiagnosed. Specifically, 86.88% of men and 84.77% of individuals 50-59 years of age with osteoporosis went undiagnosed, representing the two highest groups. DISCUSSION AND
conclusionThe substantial and increasing prevalence among certain groups and sub-groups, along with the lack of diagnostic capture of osteoporosis, highlights existing gaps in public health efforts and care delivery infrastructure. This paper highlights high-risk groups and sub-groups that may benefit most from accelerated initiatives to reduce the burden of illness associated with osteoporosis.
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