ArticleJournal of feline medicine and surgery2025
Evaluation of serum galectin-3 concentrations in healthy cats and in cats with ureteral obstruction.
Article in Journal of feline medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Urinary KIM-1 as a Marker of Renal Tubular Injury Associated with Urethral Obstruction in Non-Azotemic Cats.Animals : an open access journal from MDPI · 2026Article
- Evaluation of Cardiac Biomarkers in Lambs with White Muscle Disease.Veterinary sciences · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesSerum galectin-3 (sGal-3) is a protein present in renal tubules and increases in experimental rodent models of acute kidney injury. The aim of this study was to compare sGal-3 concentrations in healthy cats and cats with ureteral obstruction (UO).
methodsThis was a retrospective study. Banked serum was used for sGal-3 evaluations in 15 healthy control cats and 22 cats with UO. For the control cats, creatinine and symmetric dimethylarginine were within reference intervals and ultrasound showed minimal to no kidney changes. A feline-specific sGal-3 ELISA was used to determine sGal-3 concentrations. Samples were analyzed in duplicate, and results were included if the coefficient of variation between samples was <20%. Shapiro-Wilk testing was used to evaluate for normality and parametric statistics were performed.
resultsMean (±SD) sGal-3 was lower in healthy cats (274.3 ± 146.5 pg/ml) than in cats with UO (707.7 ± 223.3 pg/ml; CONCLUSIONS AND RELEVANCE: An early diagnosis of UO is critical, given its associated morbidity and mortality. Given the differences in sGal-3 concentrations in healthy cats and those with UO in this study, sGal-3 shows potential for an early UO diagnosis; however, further research is needed.
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