Evidence map›Paper›PMID 39873511›Full record

ArticlemSphere2025

c-di-GMP phosphodiesterase ProE interacts with quorum sensing protein PqsE to promote pyocyanin production in

Qishun Feng, Xin Dai, Qiulan Wu, Lianhui Zhang, Liang Yang, Yang Fu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. PqsE adapts the activity of theJournal of bacteriology · 2025
    Article
  5. Article
  6. The effect of cCMP and cUMP on growth ofFrontiers in microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qishun FengNational Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital, The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen, China.ORCID 0000-0002-4325-8250
Xin DaiSchool of Medicine, Southern University of Science and Technology, Shenzhen, China.
Qiulan WuSchool of Medicine, Southern University of Science and Technology, Shenzhen, China.
Lianhui ZhangGuangdong Province Key Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Centre, South China Agricultural University, Guangzhou, China.ORCID 0000-0002-4298-7988
Liang YangNational Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital, The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen, China.ORCID 0000-0002-2362-0128
Yang FuSchool of Medicine, Southern University of Science and Technology, Shenzhen, China.ORCID 0000-0002-5068-7248

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The universal bacterial second messenger bis-(3'-5')-cyclic dimeric guanosine monophosphate (c-di-GMP) plays critical roles in regulating a variety of bacterial functions such as biofilm formation and virulence. The metabolism of c-di-GMP is inversely controlled by diguanylate cyclases (DGCs) and phosphodiesterases (PDEs). Recently, increasing studies suggested that the protein-protein interactions between DGCs/PDEs and their partners appear to be a common way to achieve specific regulation. In this work, we showed that the PDE ProE can interact with PQS quorum sensing protein PqsE to regulate pyocyanin production in

Indexed as

Bacterial ProteinsCyclic GMPPhosphoric Diester HydrolasesPseudomonas aeruginosaPyocyanineQuorum SensingGene Expression Regulation, BacterialProtein BindingBacterial Proteinsbis(3',5')-cyclic diguanylic acidCyclic GMPPhosphoric Diester HydrolasesPyocyaninec-di-GMP phosphodiesteraseprotein-protein interactionPseudomonas aeruginosapyocyaninquorum sensing

Identifiers

PMID39873511
PMCPMC11852716

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.