Evidence map›Paper›PMID 39873509›Full record

ArticleMicrobiology spectrum2025

Inhibiting NLRP3 enhances cellular autophagy induced by outer membrane vesicles from

Jing Ge, Min Cao, Yuyao Zhang, Tianqi Wu, Jiayi Liu, Jiang Pu, Hongye He, Zhibin Guo, Shaoqing Ju, Juan Yu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. StudyingMicrobiology spectrum · 2025
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jing Ge *Department of Laboratory Medicine, Affiliated Hospital of Nantong University, Nantong, China.ORCID 0009-0002-2863-8834
Min Cao *Department of Laboratory Medicine, Affiliated Hospital of Nantong University, Nantong, China.
Yuyao Zhang *Department of Laboratory Medicine, Affiliated Hospital of Nantong University, Nantong, China.
Tianqi WuKrieger School of Arts and Science, Johns Hopkins University, Baltimore, Maryland, USA.
Jiayi LiuInstitute of Public Health, Nantong University, Nantong, China.
Jiang PuDepartment of Laboratory Medicine, Affiliated Hospital of Nantong University, Nantong, China.
Hongye HeInstitute of Public Health, Nantong University, Nantong, China.
Zhibin GuoDepartment of Laboratory Medicine, Affiliated Hospital of Nantong University, Nantong, China.
Shaoqing JuDepartment of Laboratory Medicine, Affiliated Hospital of Nantong University, Nantong, China.
Juan YuDepartment of Laboratory Medicine, Affiliated Hospital of Nantong University, Nantong, China.ORCID 0000-0003-1402-6511

Funding

College Students' Innovation and Entrepreneurship Project 202410304136YUndergraduate Innovation Traning Program of Nantong University 2022158
6 · The paper itself

Abstract

The bacterium

Indexed as

AutophagyBacterial Outer MembraneNLR Family, Pyrin Domain-Containing 3 ProteinPseudomonas aeruginosaA549 CellsAMP-Activated Protein KinasesCell LineEpithelial CellsFuransHumansIndenesInflammasomesOxidative StressPseudomonas InfectionsReactive Oxygen SpeciesSulfonamidesAMP-Activated Protein KinasesFuransIndenesInflammasomesN-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamideNLR Family, Pyrin Domain-Containing 3 ProteinNLRP3 protein, humanReactive Oxygen SpeciesSulfonamidesSulfonesautophagyinflammsomeouter membrane vesiclesPseudomonas aeruginosa

Identifiers

PMID39873509
PMCPMC11878092

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.