Evidence map›Paper›PMID 39873399›Full record

ArticleMolecular oncology2025

Respiratory complex I-mediated NAD

Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Masato HigurashiDivision of Cancer Cell Biology, Department of Pharmaceutical Sciences, Showa University Graduate School of Pharmacy, Tokyo, Japan.
Kazunori MoriDivision of Cancer Cell Biology, Department of Pharmaceutical Sciences, Showa University Graduate School of Pharmacy, Tokyo, Japan.ORCID https://orcid.org/0000-0001-7121-9956
Hidetsugu NakagawaDivision of Cancer Cell Biology, Department of Pharmaceutical Sciences, Showa University Graduate School of Pharmacy, Tokyo, Japan.
Momoko UchidaDivision of Cancer Cell Biology, Department of Pharmaceutical Sciences, Showa University Graduate School of Pharmacy, Tokyo, Japan.
Fumihiro IshikawaCenter for Biotechnology, Showa University, Tokyo, Japan.
Motoko ShibanumaDivision of Cancer Cell Biology, Department of Pharmaceutical Sciences, Showa University Graduate School of Pharmacy, Tokyo, Japan.ORCID https://orcid.org/0000-0002-8726-8047

Funding

Japan Society for the Promotion of Science 21K06809Japan Society for the Promotion of Science 22K15516
6 · The paper itself

Abstract

The role of the electron transport chain (ETC) in cell proliferation control beyond its crucial function in supporting ATP generation has recently emerged. In this study, we found that, among the four ETC complexes, the complex I (CI)-mediated NAD

Indexed as

Breast NeoplasmsCyclin-Dependent Kinase Inhibitor p21Electron Transport Complex IGene Expression Regulation, NeoplasticNADProtein BiosynthesisSirtuin 3SirtuinsTranscription, GeneticCell Line, TumorCell ProliferationFemaleHumansMCF-7 CellsCDKN1A protein, humanCyclin-Dependent Kinase Inhibitor p21Electron Transport Complex INADSIRT3 protein, humanSIRT7 protein, humanSirtuin 3Sirtuinsbreast cancerNAD+p21Cip1respiratory complex ISIRT

Identifiers

PMID39873399
PMCPMC12161471

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.